Mary Wilson
New member
March 23, 2021
DOI: 10.1056/NEJMc2102153
William Daniel[SUP] 1[/SUP], Marc Nivet[SUP] 1[/SUP], John Warner[SUP] 1[/SUP], Daniel K Podolsky[SUP] 1[/SUP]
Emergency use authorizations for two messenger RNA (mRNA) vaccines ? the BNT162b2 vaccine (Pfizer?BioNTech) and the mRNA-1273 vaccine (Moderna) ? marked important milestones in efforts to respond to the coronavirus disease 2019 (Covid-19) pandemic. These Food and Drug Administration actions were based on impressive results of clinical trials, but only in the weeks since the authorizations has real-world evidence been available to shed light on the overall effect of the vaccines on transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and related illness.
Here, we report data from the University of Texas Southwestern Medical Center (UTSW), which initiated a program on December 15, 2020, to offer vaccine against SARS-CoV-2 to its frontline employees in phase 1a of vaccination, as directed by the Texas Department of State Health Services. The launch of the vaccination effort coincided with a rapidly escalating number of new SARS-CoV-2 infections in North Texas. This escalation led to the largest surge to date in the region and strained health systems.
https://www.nejm.org/doi/full/10.1056/NEJMc2102153
DOI: 10.1056/NEJMc2102153
William Daniel[SUP] 1[/SUP], Marc Nivet[SUP] 1[/SUP], John Warner[SUP] 1[/SUP], Daniel K Podolsky[SUP] 1[/SUP]
Emergency use authorizations for two messenger RNA (mRNA) vaccines ? the BNT162b2 vaccine (Pfizer?BioNTech) and the mRNA-1273 vaccine (Moderna) ? marked important milestones in efforts to respond to the coronavirus disease 2019 (Covid-19) pandemic. These Food and Drug Administration actions were based on impressive results of clinical trials, but only in the weeks since the authorizations has real-world evidence been available to shed light on the overall effect of the vaccines on transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and related illness.
Here, we report data from the University of Texas Southwestern Medical Center (UTSW), which initiated a program on December 15, 2020, to offer vaccine against SARS-CoV-2 to its frontline employees in phase 1a of vaccination, as directed by the Texas Department of State Health Services. The launch of the vaccination effort coincided with a rapidly escalating number of new SARS-CoV-2 infections in North Texas. This escalation led to the largest surge to date in the region and strained health systems.
https://www.nejm.org/doi/full/10.1056/NEJMc2102153