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Necrotizing pneumonia associated with influenza A H1N1 infection in a child with mucopolysaccharidosis type II: Case report

tetano

Editor, Senior Moderator
Arch Argent Pediatr. 2015 Jan 1;113(1):e1-5. doi: 10.1590/S0325-00752015000100010.
[h=1][Necrotizing pneumonia associated with influenza A H1N1 infection in a child with mucopolysaccharidosis type II: Case report].[/h] [Article in Spanish]
Huillca-Huerta DA[SUP]1[/SUP], Yllescas-Estela LG[SUP]1[/SUP], Huerta-Medina EA[SUP]1[/SUP], San Mart?n-Howard PE[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Mucopolysaccharidosis type II (MPS II) is an X-linked recessive disorder characterized by a deficiency of the enzyme iduronate-2-sulfatase leading to a multisystem involvement by tissue accumulation of glycosaminoglycans heparan and dermatan sulfate. We report a case of a 9-year-old boy diagnosed with mucopolysaccharidosis type II at 4 years of age, classified as severe variant. He presented necrotizing pneumonia associated with influenza A H1N1 infection, requiring mechanical ventilation for 1 month and 10 days. This case emphasizes the importance of healthcare workers to be aware of potentially lethal complications in patients with MPS II, such as influenza A H1N1 infection, which in turn may be associated with necrotizing pneumonia.


PMID: 25622168 [PubMed - in process] Free full text

http://www.ncbi.nlm.nih.gov/pubmed/25622168
 
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