Michael Coston
Editor, Senior Moderator
Nature Med. Review: Extrapulmonary manifestations of COVID-19
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#15,358
A few examples include:
We've also seen anecdotal reports of huge increases in out-of-hospital cardiac arrests in places (NYC, Houston, etc.) where the pandemic was raging (see NBC affiliate Massive Spike in NYC ‘Cardiac Arrest’ Deaths Seen as Sign of COVID-19 Undercounting), as well as studies suggesting that COVID-19 has claimed far more lives than have been officially counted (see Netherlands RIVM: COVID-19 Incidence, Mortality & Immunity).
Most of these reports and studies have concentrated on one main system (respiratory, circulatory, CNS, etc.) or organ, providing us with isolated pieces of the puzzle. But today we have a major review - published in Nature Medicine - that brings all of those pieces together to provide a more complete picture of COVID-19 disease.
The graphic at the top of this blog - tweeted overnight by one of the study's authors - shows just how diverse COVID-19 impacts can be on the human host.
This is a detailed, lengthy review, primarily of interest to clinicians. You can read the full report at the following link:
Extrapulmonary manifestations of COVID-19
Gupta, A., Madhavan, M.V., Sehgal, K. et al. Extrapulmonary manifestations of COVID-19. Nat Med (2020). https://doi.org/10.1038/s41591-020-0968-3
Download citation
Received 29 April 2020
Barely six months into this pandemic, we are still learning about both the acute and chronic aspects of SARS-COV-2 infection. Anecdotal reports suggest a significant number of COVID-19 survivors continue to report one or more (often) debilitating symptom weeks or even months post-infection.
A story recently published by the American Heart Association News, reports:
Months after infection, many COVID-19 patients can't shake illness
By American Heart Association News
A similar report was published this past week by STAT News.
My Covid-19 symptoms have lasted more than 100 days, and I’m not alone. Will they ever end?
By YOCHAI RE'EM
JULY 8, 2020
many people continue to regard COVID-19 as a mild-to-moderate `flu-like' illness in most people, and take comfort from the notion that only 1% or 2% (of mostly elderly cases) appear to die from the infection, it may be years before we can fully tally the number of deaths, and gauge the long-term burden of disability, brought on by this pandemic.
https://afludiary.blogspot.com/2020/...pulmonary.html
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#15,358
Over the past 5 months I've highlighted literally dozens of scientific papers and reports that attest to the extraordinary systemic, extrapulmonary impact of COVID-19 on the human host. While ARDS and pneumonia are often associated with severe SARS-CoV-2 infection, other organs - including the brain, heart, and kidneys - are often involved as well.
A few examples include:
We've also seen anecdotal reports of huge increases in out-of-hospital cardiac arrests in places (NYC, Houston, etc.) where the pandemic was raging (see NBC affiliate Massive Spike in NYC ‘Cardiac Arrest’ Deaths Seen as Sign of COVID-19 Undercounting), as well as studies suggesting that COVID-19 has claimed far more lives than have been officially counted (see Netherlands RIVM: COVID-19 Incidence, Mortality & Immunity).
Most of these reports and studies have concentrated on one main system (respiratory, circulatory, CNS, etc.) or organ, providing us with isolated pieces of the puzzle. But today we have a major review - published in Nature Medicine - that brings all of those pieces together to provide a more complete picture of COVID-19 disease.
The graphic at the top of this blog - tweeted overnight by one of the study's authors - shows just how diverse COVID-19 impacts can be on the human host.
This is a detailed, lengthy review, primarily of interest to clinicians. You can read the full report at the following link:
Extrapulmonary manifestations of COVID-19
Gupta, A., Madhavan, M.V., Sehgal, K. et al. Extrapulmonary manifestations of COVID-19. Nat Med (2020). https://doi.org/10.1038/s41591-020-0968-3
Download citation
Received 29 April 2020
Accepted 05 June 2020
Barely six months into this pandemic, we are still learning about both the acute and chronic aspects of SARS-COV-2 infection. Anecdotal reports suggest a significant number of COVID-19 survivors continue to report one or more (often) debilitating symptom weeks or even months post-infection.
A story recently published by the American Heart Association News, reports:
Months after infection, many COVID-19 patients can't shake illness
By American Heart Association News
A similar report was published this past week by STAT News.
My Covid-19 symptoms have lasted more than 100 days, and I’m not alone. Will they ever end?
By YOCHAI RE'EM
JULY 8, 2020
many people continue to regard COVID-19 as a mild-to-moderate `flu-like' illness in most people, and take comfort from the notion that only 1% or 2% (of mostly elderly cases) appear to die from the infection, it may be years before we can fully tally the number of deaths, and gauge the long-term burden of disability, brought on by this pandemic.
https://afludiary.blogspot.com/2020/...pulmonary.html