Shiloh
Editor, Senior Moderator
Source: https://www.studyfinds.org/nasal-spray-may-cure-dementia/
Nasal spray combination of rifampicin, resveratrol could cure dementia
December 31, 2021
by Study Finds
OSAKA, Japan — A nasal spray that combines the powers of two drugs may be able to treat and even prevent Alzheimer’s disease, the most common form of dementia. Researchers from Osaka City University say the potentially groundbreaking treatment combines an antibiotic called rifampicin with resveratrol — an antioxidant found in plants.
Their study reports that experiments involving mice were so encouraging, global clinical trials are already in the planning phase. Scientists genetically engineered the animals to develop Alzheimer’s, frontotemporal dementia, or dementia with Lewy bodies — three of the main forms of the disease.
Cognitive skills in the mice dramatically improved after the team injected the chemical cocktail into their noses five times a week for four weeks. Tests after the treatment revealed that the rodents had fewer toxic proteins called amyloid beta and tau, both of which play a major role in the development of dementia onset.
Communication between neurons also improved after the spray restored synapses that connect these brain nerve cells...
Nasal spray combination of rifampicin, resveratrol could cure dementia
December 31, 2021
by Study Finds
OSAKA, Japan — A nasal spray that combines the powers of two drugs may be able to treat and even prevent Alzheimer’s disease, the most common form of dementia. Researchers from Osaka City University say the potentially groundbreaking treatment combines an antibiotic called rifampicin with resveratrol — an antioxidant found in plants.
Their study reports that experiments involving mice were so encouraging, global clinical trials are already in the planning phase. Scientists genetically engineered the animals to develop Alzheimer’s, frontotemporal dementia, or dementia with Lewy bodies — three of the main forms of the disease.
Cognitive skills in the mice dramatically improved after the team injected the chemical cocktail into their noses five times a week for four weeks. Tests after the treatment revealed that the rodents had fewer toxic proteins called amyloid beta and tau, both of which play a major role in the development of dementia onset.
Communication between neurons also improved after the spray restored synapses that connect these brain nerve cells...