Microbiology Independent Research Journal
Volume 2, Number 1, 2015
Mutations in human genes that increase the risk for severe influenza infection
O. I. Kiselev[SUP]1[/SUP] , A. B. Komissarov[SUP]1[/SUP] , O.S.Konshina[SUP]1#[/SUP] , M.N.Dmitrieva[SUP]1[/SUP] , E.G.Deyeva[SUP]1[/SUP] , T.V.Sologub[SUP]1[/SUP] , V.I.Pokrovskiy[SUP]2[/SUP]
Author Affiliations
[SUP]1[/SUP] Research Institute of Influenza, Saint Petersburg, Russian Federation
[SUP]2[/SUP] Central Research Institute of Epidemiology, Moscow, Russian Federation
[SUP]#[/SUP] Corresponding author: Olga Konshina, 197376, St. Petersburg, Prof. Popova str., 15/17, E-mail:
olga_konshina@influenza.spb.ru
Abstract
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The system of genetic control of innate immune responses to influenza infection and gene function allows for the development of systemic treatment of influenza with a focus on the phenotype of mutations based on individual genetic susceptibility to severe disease and/or the development of complications.
