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Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin an

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Editor, Senior Moderator
Arch Virol. 2016 Jan 2. [Epub ahead of print]
[h=1]Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes.[/h] Chen D[SUP]1[/SUP], Wen X[SUP]2[/SUP], Sun Y[SUP]3[/SUP], Mao H[SUP]4[/SUP], Zhang Y[SUP]4[/SUP], Chen Y[SUP]4[/SUP], Wang X[SUP]4[/SUP], Sun B[SUP]1[/SUP], Wang X[SUP]1[/SUP], Zhang X[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China.


[h=4]KEYWORDS:[/h] Influenza B virus; Molecular epidemiology; Phylogenetic; Victoria; Yamagata

PMID: 26724821 [PubMed - as supplied by publisher]
 
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