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Mult Scler Relat Disord . Fulminant neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccination: A need for reconsideration?

tetano

Editor, Senior Moderator
Mult Scler Relat Disord


. 2022 Jul 5;66:104035.
doi: 10.1016/j.msard.2022.104035. Online ahead of print.
Fulminant neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccination: A need for reconsideration?


Ali Motahharynia[SUP] 1 [/SUP], Saba Naghavi[SUP] 2 [/SUP], Vahid Shaygannejad[SUP] 2 [/SUP], Iman Adibi[SUP] 3 [/SUP]



Affiliations

Abstract

During the coronavirus disease 2019 (COVID-19) pandemic, mass vaccination was a beneficial strategy in many countries. Nevertheless, reports of serious complications such as postvaccination neuromyelitis optica spectrum disorder (NMOSD) raised concerns about the safety of vaccines. Anamnart and colleagues explained postvaccination NMOSD following different vaccines, including COVID-19. To emphasize the message of this article, in this letter, we present a unique case of postvaccination NMOSD with a fulminant and fatal course, which may show a plausible relationship between COVID-19 vaccination and triggering anti-aquaporin-4 antibody (AQP4-Ab).

Keywords: COVID-19 vaccine; NMOSD; Neuromyelitis optica spectrum disorder; Postvaccination.
 
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