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mSphere . Building-level wastewater surveillance localizes interseasonal influenza variation

tetano

Editor, Senior Moderator
mSphere


. 2024 Jan 3:e0060023.
doi: 10.1128/msphere.00600-23. Online ahead of print. Building-level wastewater surveillance localizes interseasonal influenza variation

Emma R Germano[SUP] 1 [/SUP], Tiffany Flores[SUP] 1 [/SUP], Grace S Freed[SUP] #[/SUP][SUP] 1 [/SUP], Kang Kim[SUP] #[/SUP][SUP] 1 [/SUP], Grace H Tulinsky[SUP] #[/SUP][SUP] 2 [/SUP], Annie Yang[SUP] #[/SUP][SUP] 2 [/SUP], Oliver J Rose[SUP] 3 [/SUP], Caroline A Ray[SUP] 4 [/SUP], April Autry[SUP] 4 5 [/SUP], Marina Catallozzi[SUP] 4 5 6 [/SUP], Brian J Mailloux[SUP] 2 [/SUP], Jj L Miranda[SUP] 1 [/SUP]



Affiliations
Free article Abstract

Seasonal influenza remains a major public health burden. We monitored influenza A in dormitory wastewater of a New York City college in 2021 and 2022. Longitudinal samples acquired over consecutive years allowed measurement of individual buildings between seasons. We uncovered building-level changes in the magnitude and timing of test positivity concordant with clinical cases. Surveillance also localized the heterogeneity of influenza variation during the large 2022 seasonal surge. The ability to detect such changes could be leveraged as part of a public health response.

Keywords: New York City; influenza A virus; students; wastewater; wastewater-based epidemiological monitoring.

 
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