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Mpox virus resurgence in New York City, 2024 - Virological

M

Mary Wilson

Well-known member
June 10 2024
jwertheim​

New York City (NYC) experienced a large mpox outbreak in 2022, with 3821 cases. Case counts remained low through most of 2023 at only 184 cases, a mean of 3.5 cases per week. However, incidence increased in 2024, with 191 cases as of 4 May 2024, a mean of 10.6 cases per week. To investigate the evolutionary dynamics underlying this increase in case count, we performed phylogenetic and phylodynamic analysis of the 81 mpox virus (MPXV) genomes sampled in 2023 and 2024 in NYC, sequenced by the NYC Public Health Labs (PHL), in the context of the global MPXV diversity published on NCBI and GISAID as of 30 May 2024.

Of the 113 NYC MPXV genomes sampled from people diagnosed with mpox at sexual health clinics between January 2023 through April 2024, 81 are from unique individuals (32 of these genomes are from a second sequenced swab from the same person) representing 21.6% of NYC mpox cases; 38 genomes were sampled in 2023 and 43 in 2024. ...

https://virological.org/t/mpox-virus-resurgence-in-new-york-city-2024/973
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