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Monkeypox virus genome sequences from multiple lesions indicates co-infection of a UK returning traveller - Virological

Mary Wilson

Well-known member
June 23 2022

Ana da Silva Filipe[SUP]1[/SUP], Lily Tong[SUP]1*[/SUP], Vattipally B Sreenu[SUP]1*[/SUP], Alasdair Maclean[SUP]2[/SUP], Rory Gunson[SUP]2[/SUP], Matthew TG Holden[SUP]3,4[/SUP], David Barr[SUP]5[/SUP], Antonia Ho[SUP]1[/SUP], Massimo Palmarini[SUP]1[/SUP], Andrew Rambaut[SUP]6[/SUP], David L Robertson[SUP]1[/SUP], Emma C Thomson[SUP]1[/SUP]

... Here we report five MPXV genome sequences from an infected person presenting with rash and fever in May 2022, and reporting a single exposure event following recent travel to Germany. The patient was recruited to the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study. Ethical approval was given by the South Central–Oxford C Research Ethics Committee in England (13/SC/0149), the Scotland A Research Ethics Committee (20/SS/0028), and the WHO Ethics Review Committee (RPC571 and RPC572).

Genome sequencing was carried out on samples from five different lesions from the same patient: CVR_MPXV1a, CVR_MPXV1b, CVR_MPXV1c, CVR_MPXV1d and CVR_MPXV1e. ...

https://virological.org/t/monkeypox...-co-infection-of-a-uk-returning-traveller/873
 
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