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Modelled seasonal influenza mortality shows marked differences in risk by age, sex, ethnicity and socioeconomic position in New Zealand

tetano

Editor, Senior Moderator
J Infect. 2017 Jun 1. pii: S0163-4453(17)30165-2. doi: 10.1016/j.jinf.2017.05.017. [Epub ahead of print]
[h=1]Modelled seasonal influenza mortality shows marked differences in risk by age, sex, ethnicity and socioeconomic position in New Zealand.[/h] Khieu TQT[SUP]1[/SUP], Pierse N[SUP]2[/SUP], Telfar-Barnard LF[SUP]2[/SUP], Zhang J[SUP]2[/SUP], Huang QS[SUP]3[/SUP], Baker MG[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] Influenza is responsible for a large number of deaths which can only be estimated using modelling methods. Such methods have rarely been applied to describe the major socio-demographic characteristics of this disease burden.
[h=4]METHODS:[/h] We used quasi Poisson regression models with weekly counts of deaths and isolates of influenza A, B and respiratory syncytial virus for the period 1994 to 2008.
[h=4]RESULTS:[/h] The estimated average mortality rate was 13.5 per 100,000 people which was 1.8% of all deaths in New Zealand. Influenza mortality differed markedly by age, sex, ethnicity and socioeconomic position. Relatively vulnerable groups were males aged 65-79 years (Rate ratio (RR)=1.9, 95% CI: 1.9, 1.9 compared with females), Māori (RR=3.6, 95% CI: 3.6, 3.7 compared with European/Others aged 65-79 years), Pacific (RR=2.4, 95% CI: 2.4, 2.4 compared with European/Others aged 65-79 years) and those living in the most deprived areas (RR=1.8, 95% CI: 1.3, 2.4) for New Zealand Deprivation (NZDep) 9&10 (the most deprived) compared with NZDep 1&2 (the least deprived).
[h=4]CONCLUSIONS:[/h] These results support targeting influenza vaccination and other interventions to the most vulnerable groups, in particular Māori and Pacific people and men aged 65-79 years and those living in the most deprived areas.
Copyright ? 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.


[h=4]KEYWORDS:[/h] influenza; mortality; regression model; virus

PMID: 28579304 DOI: 10.1016/j.jinf.2017.05.017
 
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