tetano
Editor, Senior Moderator
Mod Rheumatol Case Rep
. 2023 Jan 27;rxad008.
doi: 10.1093/mrcr/rxad008. Online ahead of print.
Two cases of systemic lupus erythematosus (SLE) after administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
Mayu Sakai[SUP] 1 [/SUP], Ken Takao[SUP] 1 [/SUP], Masami Mizuno[SUP] 1 [/SUP], Hironori Ando[SUP] 1 [/SUP], Yui Kawashima[SUP] 1 [/SUP], Takehiro Kato[SUP] 1 [/SUP], Saki Kubota[SUP] 1 2 [/SUP], Tokuyuki Hirose[SUP] 1 [/SUP], Takuo Hirota[SUP] 1 [/SUP], Yukio Horikawa[SUP] 1 [/SUP], Daisuke Yabe[SUP] 1 2 3 4 [/SUP]
Affiliations
Abstract
Although there is great demand for increased COVID-19 vaccination worldwide, rare side effects of the vaccines in susceptible individuals are attracting attention. We recently treated two patients who developed SLE after administration of a SARS-CoV-2 vaccine from Pfizer-BioNTech or Moderna. While causal relationships between vaccination and adverse events are difficult to discern due to both confounding and masking factors, our findings suggest that attention to possible adjuvant-related autoimmune diseases in certain individuals receiving SARS-CoV-2 vaccines is appropriate.
Keywords: Coronavirus Disease 2019; Systemic lupus erythematosus; vaccination.
. 2023 Jan 27;rxad008.
doi: 10.1093/mrcr/rxad008. Online ahead of print.
Two cases of systemic lupus erythematosus (SLE) after administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
Mayu Sakai[SUP] 1 [/SUP], Ken Takao[SUP] 1 [/SUP], Masami Mizuno[SUP] 1 [/SUP], Hironori Ando[SUP] 1 [/SUP], Yui Kawashima[SUP] 1 [/SUP], Takehiro Kato[SUP] 1 [/SUP], Saki Kubota[SUP] 1 2 [/SUP], Tokuyuki Hirose[SUP] 1 [/SUP], Takuo Hirota[SUP] 1 [/SUP], Yukio Horikawa[SUP] 1 [/SUP], Daisuke Yabe[SUP] 1 2 3 4 [/SUP]
Affiliations
- PMID: 36715089
- DOI: 10.1093/mrcr/rxad008
Abstract
Although there is great demand for increased COVID-19 vaccination worldwide, rare side effects of the vaccines in susceptible individuals are attracting attention. We recently treated two patients who developed SLE after administration of a SARS-CoV-2 vaccine from Pfizer-BioNTech or Moderna. While causal relationships between vaccination and adverse events are difficult to discern due to both confounding and masking factors, our findings suggest that attention to possible adjuvant-related autoimmune diseases in certain individuals receiving SARS-CoV-2 vaccines is appropriate.
Keywords: Coronavirus Disease 2019; Systemic lupus erythematosus; vaccination.