tetano
Editor, Senior Moderator
Mod Rheumatol Case Rep
. 2022 Oct 28;rxac085.
doi: 10.1093/mrcr/rxac085. Online ahead of print.
Possible case of polyarteritis nodosa with epididymitis following COVID-19 vaccination: A case report and review of the literature
Yusuke Ohkubo[SUP] 1 [/SUP], Shin-Ichiro Ohmura[SUP] 1 [/SUP], Ryuhei Ishihara[SUP] 1 [/SUP], Toshiaki Miyamoto[SUP] 1 [/SUP]
Affiliations
Abstract
The global outbreak of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 has prompted the rapid spread and development of vaccines to prevent the spread of the disease. COVID-19 vaccine has demonstrated excellent efficacy in reducing morbidity and severity of the disease, and most adverse reactions are very minor. However, some patients have been reported to develop autoimmune diseases, such as rheumatoid arthritis, myocarditis, Guillain-Barre syndrome, and vasculitis, following COVID-19 vaccination. Herein, we present a case of polyarteritis nodosa with epididymitis following COVID-19 mRNA vaccination. The patient's initial symptoms were fever and testicular pain, and magnetic resonance imaging showed epididymitis. He was diagnosed as having polyarteritis nodosa with epididymitis and treated with high-dose prednisolone, with a good clinical outcome.
Keywords: COVID-19; autoimmune phenomena; epididymitis; mRNA vaccine; polyarteritis nodosa.
. 2022 Oct 28;rxac085.
doi: 10.1093/mrcr/rxac085. Online ahead of print.
Possible case of polyarteritis nodosa with epididymitis following COVID-19 vaccination: A case report and review of the literature
Yusuke Ohkubo[SUP] 1 [/SUP], Shin-Ichiro Ohmura[SUP] 1 [/SUP], Ryuhei Ishihara[SUP] 1 [/SUP], Toshiaki Miyamoto[SUP] 1 [/SUP]
Affiliations
- PMID: 36305628
- DOI: 10.1093/mrcr/rxac085
Abstract
The global outbreak of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 has prompted the rapid spread and development of vaccines to prevent the spread of the disease. COVID-19 vaccine has demonstrated excellent efficacy in reducing morbidity and severity of the disease, and most adverse reactions are very minor. However, some patients have been reported to develop autoimmune diseases, such as rheumatoid arthritis, myocarditis, Guillain-Barre syndrome, and vasculitis, following COVID-19 vaccination. Herein, we present a case of polyarteritis nodosa with epididymitis following COVID-19 mRNA vaccination. The patient's initial symptoms were fever and testicular pain, and magnetic resonance imaging showed epididymitis. He was diagnosed as having polyarteritis nodosa with epididymitis and treated with high-dose prednisolone, with a good clinical outcome.
Keywords: COVID-19; autoimmune phenomena; epididymitis; mRNA vaccine; polyarteritis nodosa.