tetano
Editor, Senior Moderator
mLife
. 2026 Mar 30;5(2):259-262.
doi: 10.1002/mlf2.12122. eCollection 2026 Apr.
An infection and pathogenesis mouse model of SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR)
Lai Wei[SUP] 1 [/SUP], Shuiqing Liu[SUP] 1 [/SUP], Shanshan Lu[SUP] 1 [/SUP], Shengdong Luo[SUP] 2 [/SUP], Xiaoping An[SUP] 1 [/SUP], Huahao Fan[SUP] 1 [/SUP], Erguang Li[SUP] 3 [/SUP], Lihua Song[SUP] 1 [/SUP]
Affiliations
SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR) is highly attenuated, but can cause mortality in a specifically designed human ACE2-transgenic mouse model, making it a surrogate model for evaluating the efficacy of vaccines and drugs against SARS-CoV-2.
© 2026 The Authors. mLife published by John Wiley & Sons Australia, Ltd on behalf of Institu
. 2026 Mar 30;5(2):259-262.
doi: 10.1002/mlf2.12122. eCollection 2026 Apr.
An infection and pathogenesis mouse model of SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR)
Lai Wei[SUP] 1 [/SUP], Shuiqing Liu[SUP] 1 [/SUP], Shanshan Lu[SUP] 1 [/SUP], Shengdong Luo[SUP] 2 [/SUP], Xiaoping An[SUP] 1 [/SUP], Huahao Fan[SUP] 1 [/SUP], Erguang Li[SUP] 3 [/SUP], Lihua Song[SUP] 1 [/SUP]
Affiliations
- PMID: 42079448
- PMCID: PMC13131323
- DOI: 10.1002/mlf2.12122
SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR) is highly attenuated, but can cause mortality in a specifically designed human ACE2-transgenic mouse model, making it a surrogate model for evaluating the efficacy of vaccines and drugs against SARS-CoV-2.
© 2026 The Authors. mLife published by John Wiley & Sons Australia, Ltd on behalf of Institu