tetano
Editor, Senior Moderator
Pediatr Infect Dis J. 2011 Jan 4. [Epub ahead of print]
MIXTURES OF OSELTAMIVIR-SENSITIVE AND -RESISTANT PANDEMIC INFLUENZA A/H1N1/2009 VIRUSES IN IMMUNOCOMPROMISED HOSPITALIZED CHILDREN.
Suhaila M, Tang JW, Lee HK, Lin C, Tambyah PA, Yap HK, Quak SH, Koay ES.
From the *Departments of Paediatrics, National University of Singapore, Singapore; ?Department of Laboratory Medicine, National University Hospital, Singapore; ?National Public Health Laboratory, Singapore; and Departments of ?Medicine and ?Pathology, National University of Singapore, Singapore.
Abstract
We report on 3 immunocompromised children infected with pandemic influenza A/H1N1/2009 in whom mixtures of oseltamivir-susceptible and oseltamivir-resistant viral populations developed, despite them receiving relatively short-term courses of oseltamivir. In addition, it was found that bacterial coinfections were common, indicating that empiric, antibiotics should be considered in such patients when infected with influenza virus.
PMID: 21206398 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21206398
MIXTURES OF OSELTAMIVIR-SENSITIVE AND -RESISTANT PANDEMIC INFLUENZA A/H1N1/2009 VIRUSES IN IMMUNOCOMPROMISED HOSPITALIZED CHILDREN.
Suhaila M, Tang JW, Lee HK, Lin C, Tambyah PA, Yap HK, Quak SH, Koay ES.
From the *Departments of Paediatrics, National University of Singapore, Singapore; ?Department of Laboratory Medicine, National University Hospital, Singapore; ?National Public Health Laboratory, Singapore; and Departments of ?Medicine and ?Pathology, National University of Singapore, Singapore.
Abstract
We report on 3 immunocompromised children infected with pandemic influenza A/H1N1/2009 in whom mixtures of oseltamivir-susceptible and oseltamivir-resistant viral populations developed, despite them receiving relatively short-term courses of oseltamivir. In addition, it was found that bacterial coinfections were common, indicating that empiric, antibiotics should be considered in such patients when infected with influenza virus.
PMID: 21206398 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21206398