tetano
Editor, Senior Moderator
Microorganisms
. 2021 Jan 22;9(2):232.
doi: 10.3390/microorganisms9020232.
A Comprehensive Review of Detection Methods for SARS-CoV-2
Aziz Eftekhari[SUP] 1 [/SUP], Mahdieh Alipour[SUP] 2 [/SUP], Leila Chodari[SUP] 3 [/SUP], Solmaz Maleki Dizaj[SUP] 2 [/SUP], Mohammadreza Ardalan[SUP] 4 [/SUP], Mohammad Samiei[SUP] 5 [/SUP], Simin Sharifi[SUP] 2 [/SUP], Sepideh Zununi Vahed[SUP] 4 [/SUP], Irada Huseynova[SUP] 6 [/SUP], Rovshan Khalilov[SUP] 7 8 [/SUP], Elham Ahmadian[SUP] 4 [/SUP], Magali Cucchiarini[SUP] 9 [/SUP]
Affiliations
Abstract
Recently, the outbreak of the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, in China and its subsequent spread across the world has caused numerous infections and deaths and disrupted normal social activity. Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. In this paper, we summarize promising methods, such as reverse transcription-polymerase chain reaction (RT-PCR), serological testing, point-of-care testing, smartphone surveillance of infectious diseases, nanotechnology-based approaches, biosensors, amplicon-based metagenomic sequencing, smartphone, and wastewater-based epidemiology (WBE) that can also be utilized for the detection of SARS-CoV-2. In addition, we discuss principles, advantages, and disadvantages of these detection methods, and highlight the potential methods for the development of additional techniques and products for early and fast detection of SARS-CoV-2.
Keywords: COVID-19; coronavirus; detection; epidemic; nanotechnology.
. 2021 Jan 22;9(2):232.
doi: 10.3390/microorganisms9020232.
A Comprehensive Review of Detection Methods for SARS-CoV-2
Aziz Eftekhari[SUP] 1 [/SUP], Mahdieh Alipour[SUP] 2 [/SUP], Leila Chodari[SUP] 3 [/SUP], Solmaz Maleki Dizaj[SUP] 2 [/SUP], Mohammadreza Ardalan[SUP] 4 [/SUP], Mohammad Samiei[SUP] 5 [/SUP], Simin Sharifi[SUP] 2 [/SUP], Sepideh Zununi Vahed[SUP] 4 [/SUP], Irada Huseynova[SUP] 6 [/SUP], Rovshan Khalilov[SUP] 7 8 [/SUP], Elham Ahmadian[SUP] 4 [/SUP], Magali Cucchiarini[SUP] 9 [/SUP]
Affiliations
- PMID: 33499379
- DOI: 10.3390/microorganisms9020232
Abstract
Recently, the outbreak of the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, in China and its subsequent spread across the world has caused numerous infections and deaths and disrupted normal social activity. Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. In this paper, we summarize promising methods, such as reverse transcription-polymerase chain reaction (RT-PCR), serological testing, point-of-care testing, smartphone surveillance of infectious diseases, nanotechnology-based approaches, biosensors, amplicon-based metagenomic sequencing, smartphone, and wastewater-based epidemiology (WBE) that can also be utilized for the detection of SARS-CoV-2. In addition, we discuss principles, advantages, and disadvantages of these detection methods, and highlight the potential methods for the development of additional techniques and products for early and fast detection of SARS-CoV-2.
Keywords: COVID-19; coronavirus; detection; epidemic; nanotechnology.