tetano
Editor, Senior Moderator
Microbiol Spectr
. 2022 Apr 21;e0064322.
doi: 10.1128/spectrum.00643-22. Online ahead of print.
Highly Pathogenic Avian Influenza A(H5Nx) Virus of Clade 2.3.4.4b Emerging in Tibet, China, 2021
Yi Li[SUP] #[/SUP][SUP] 1 [/SUP], Xiang Li[SUP] #[/SUP][SUP] 1 [/SUP], Xinru Lv[SUP] #[/SUP][SUP] 1 [/SUP], Qiuzi Xu[SUP] 1 [/SUP], Zhenliang Zhao[SUP] 1 [/SUP], Siyuan Qin[SUP] 2 [/SUP], Peng Peng[SUP] 2 [/SUP], Fengyi Qu[SUP] 1 [/SUP], Rongxiu Qin[SUP] 1 [/SUP], Qing An[SUP] 1 [/SUP], Meixi Wang[SUP] 1 [/SUP], Zhen Zhang[SUP] 1 [/SUP], Hua Luo[SUP] 1 [/SUP], Xiangwei Zeng[SUP] 1 [/SUP], Yulong Wang[SUP] 1 [/SUP], Zhijun Hou[SUP] 1 [/SUP], Heting Sun[SUP] 2 [/SUP], Yajun Wang[SUP] 1 [/SUP], Yu Xu[SUP] 2 [/SUP], Yanbing Li[SUP] 3 [/SUP], Hongliang Chai[SUP] 1 [/SUP]
Affiliations
Abstract
H5N8 and H5N1 highly pathogenic avian influenza viruses (AIVs) of clade 2.3.4.4b were isolated from dead migratory birds and fecal samples collected in Tibet, China, in May 2021. Phylogenetic analyses showed that the viruses isolated in this study may have spread from wintering or stopover grounds of migratory birds in South Asia. We monitored two disparate clade 2.3.4.4b H5Nx viruses in migratory birds in Tibet during their breeding season. The data revealed that breeding grounds may exhibit a potential pooling effect among avian influenza viruses in different migratory populations. IMPORTANCE In this study, 15 H5N8 and two H5N1 highly pathogenic avian influenza viruses of clade 2.3.4.4b were isolated from dead migratory birds and fecal samples in Tibet, China. Isolates of H5N1 virus of clade 2.3.4.4b have been rarely reported in China. Our findings highlight that breeding grounds may exhibit a potential pooling effect among avian influenza viruses (AIVs) in different migratory populations. In addition to intensification of the surveillance of AIVs in migratory birds in Tibet, China, international cooperation should be strengthened.
Keywords: H5N1; H5N8; HPAIV; clade 2.3.4.4b; migratory birds.
. 2022 Apr 21;e0064322.
doi: 10.1128/spectrum.00643-22. Online ahead of print.
Highly Pathogenic Avian Influenza A(H5Nx) Virus of Clade 2.3.4.4b Emerging in Tibet, China, 2021
Yi Li[SUP] #[/SUP][SUP] 1 [/SUP], Xiang Li[SUP] #[/SUP][SUP] 1 [/SUP], Xinru Lv[SUP] #[/SUP][SUP] 1 [/SUP], Qiuzi Xu[SUP] 1 [/SUP], Zhenliang Zhao[SUP] 1 [/SUP], Siyuan Qin[SUP] 2 [/SUP], Peng Peng[SUP] 2 [/SUP], Fengyi Qu[SUP] 1 [/SUP], Rongxiu Qin[SUP] 1 [/SUP], Qing An[SUP] 1 [/SUP], Meixi Wang[SUP] 1 [/SUP], Zhen Zhang[SUP] 1 [/SUP], Hua Luo[SUP] 1 [/SUP], Xiangwei Zeng[SUP] 1 [/SUP], Yulong Wang[SUP] 1 [/SUP], Zhijun Hou[SUP] 1 [/SUP], Heting Sun[SUP] 2 [/SUP], Yajun Wang[SUP] 1 [/SUP], Yu Xu[SUP] 2 [/SUP], Yanbing Li[SUP] 3 [/SUP], Hongliang Chai[SUP] 1 [/SUP]
Affiliations
- PMID: 35446151
- DOI: 10.1128/spectrum.00643-22
Abstract
H5N8 and H5N1 highly pathogenic avian influenza viruses (AIVs) of clade 2.3.4.4b were isolated from dead migratory birds and fecal samples collected in Tibet, China, in May 2021. Phylogenetic analyses showed that the viruses isolated in this study may have spread from wintering or stopover grounds of migratory birds in South Asia. We monitored two disparate clade 2.3.4.4b H5Nx viruses in migratory birds in Tibet during their breeding season. The data revealed that breeding grounds may exhibit a potential pooling effect among avian influenza viruses in different migratory populations. IMPORTANCE In this study, 15 H5N8 and two H5N1 highly pathogenic avian influenza viruses of clade 2.3.4.4b were isolated from dead migratory birds and fecal samples in Tibet, China. Isolates of H5N1 virus of clade 2.3.4.4b have been rarely reported in China. Our findings highlight that breeding grounds may exhibit a potential pooling effect among avian influenza viruses (AIVs) in different migratory populations. In addition to intensification of the surveillance of AIVs in migratory birds in Tibet, China, international cooperation should be strengthened.
Keywords: H5N1; H5N8; HPAIV; clade 2.3.4.4b; migratory birds.
