tetano
Editor, Senior Moderator
Microb Pathog
. 2020 Nov 3;104554.
doi: 10.1016/j.micpath.2020.104554. Online ahead of print.
Immunopathological similarities between COVID-19 and influenza: Investigating the consequences of Co-infection
Hossein Khorramdelazad[SUP] 1 [/SUP], Mohammad Hossein Kazemi[SUP] 2 [/SUP], Alireza Najafi[SUP] 3 [/SUP], Maryam Keykhaee[SUP] 4 [/SUP], Reza Zolfaghari Emameh[SUP] 5 [/SUP], Reza Falak[SUP] 6 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a global public health emergency since December 2019, and so far, more than 980,000 people (until September 24, 2020) around the world have died. SARS-CoV-2 mimics the influenza virus regarding methods and modes of transmission, clinical features, related immune responses, and seasonal coincidence. Accordingly, co-infection by these viruses is imaginable because some studies have reported several cases with SARS-CoV-2 and influenza virus co-infection. Given the importance of the mentioned co-infection and the coming influenza season, it is essential to recognize the similarities and differences between the symptoms and pathogenesis of these two viruses and immunopathogenesis and treatment of SARS-CoV-2 and influenza virus. Therefore, we reviewed the virology, clinical features, and immunopathogenesis of both influenza virus and SARS-CoV-2 and evaluated outcomes in cases with SARS-CoV-2 and influenza virus co-infection.
Keywords: COVID-19; Co-infection; Influenza; Pathogenesis; SARS-COV2.
. 2020 Nov 3;104554.
doi: 10.1016/j.micpath.2020.104554. Online ahead of print.
Immunopathological similarities between COVID-19 and influenza: Investigating the consequences of Co-infection
Hossein Khorramdelazad[SUP] 1 [/SUP], Mohammad Hossein Kazemi[SUP] 2 [/SUP], Alireza Najafi[SUP] 3 [/SUP], Maryam Keykhaee[SUP] 4 [/SUP], Reza Zolfaghari Emameh[SUP] 5 [/SUP], Reza Falak[SUP] 6 [/SUP]
Affiliations
- PMID: 33157216
- DOI: 10.1016/j.micpath.2020.104554
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a global public health emergency since December 2019, and so far, more than 980,000 people (until September 24, 2020) around the world have died. SARS-CoV-2 mimics the influenza virus regarding methods and modes of transmission, clinical features, related immune responses, and seasonal coincidence. Accordingly, co-infection by these viruses is imaginable because some studies have reported several cases with SARS-CoV-2 and influenza virus co-infection. Given the importance of the mentioned co-infection and the coming influenza season, it is essential to recognize the similarities and differences between the symptoms and pathogenesis of these two viruses and immunopathogenesis and treatment of SARS-CoV-2 and influenza virus. Therefore, we reviewed the virology, clinical features, and immunopathogenesis of both influenza virus and SARS-CoV-2 and evaluated outcomes in cases with SARS-CoV-2 and influenza virus co-infection.
Keywords: COVID-19; Co-infection; Influenza; Pathogenesis; SARS-COV2.