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Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection

tetano

tetano

Editor, Senior Moderator
Indian J Nephrol. 2014 Mar;24(2):114-6. doi: 10.4103/0971-4065.127902.
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection.
Kute VB1, Vanikar AV2, Shah PR1, Gumber MR1, Patel HV1, Trivedi HL1.
Author information
Abstract

Respiratory complications and renal failure are the leading causes for morbidity and mortality due to influenza (H1N1) virus infection. There has been limited information on histopathology of H1N1 influenza-related acute kidney injury (AKI). We describe AKI with H1N1 infection in a 52-year-old female. Renal biopsy showed mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis. Her condition improved rapidly with oseltamivir, fluid replacement, steroid and dialysis. Our case suggests that H1N1 infection may have a causative link to the development of mesangial proliferative glomerulonephritis with acute tubulointerstitial nephritis.
KEYWORDS:

Acute kidney injury, H1N1 influenza, glomerulonephritis, histopathology

PMID:
24701045
[PubMed]
PMCID:
PMC3968599

Free PMC Article

http://www.ncbi.nlm.nih.gov/pubmed/24701045
 
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