tetano
Editor, Senior Moderator
Mem Inst Oswaldo Cruz
. 2020;115:e200225.
doi: 10.1590/0074-02760200225. Epub 2020 Aug 14.
Low risk of serological cross-reactivity between dengue and COVID-19
Michele Spinicci[SUP] 1 [/SUP], Alessandro Bartoloni[SUP] 1 [/SUP], Antonia Mantella[SUP] 1 [/SUP], Lorenzo Zammarchi[SUP] 1 [/SUP], Gian Maria Rossolini[SUP] 1 [/SUP], Alberto Antonelli[SUP] 1 [/SUP]
Affiliations
Abstract
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
. 2020;115:e200225.
doi: 10.1590/0074-02760200225. Epub 2020 Aug 14.
Low risk of serological cross-reactivity between dengue and COVID-19
Michele Spinicci[SUP] 1 [/SUP], Alessandro Bartoloni[SUP] 1 [/SUP], Antonia Mantella[SUP] 1 [/SUP], Lorenzo Zammarchi[SUP] 1 [/SUP], Gian Maria Rossolini[SUP] 1 [/SUP], Alberto Antonelli[SUP] 1 [/SUP]
Affiliations
- PMID: 32813814
- DOI: 10.1590/0074-02760200225
Abstract
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.