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Medicine (Baltimore) . Association between clinical characteristics and CT findings in patients with coronavirus disease-2019

tetano

Editor, Senior Moderator
Medicine (Baltimore)


. 2021 Nov 5;100(44):e27435.
doi: 10.1097/MD.0000000000027435.
Association between clinical characteristics and CT findings in patients with coronavirus disease-2019


Ting Zheng[SUP] 1 [/SUP], Hao Ren[SUP] 2 [/SUP], Yongjuan Wu[SUP] 2 [/SUP], Jiangtao Wang[SUP] 2 [/SUP]



Affiliations

Abstract

This retrospective study was to investigate the association between clinical characteristics and computerized tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19). The clinical data of COVID-19 patients were retrospectively analyzed. Spearman correlation analysis was used to identify the correlation. Totally 209 consecutive COVID-19 patients were eligible for the study, with the mean age of 47.53 ± 13.52 years. At onset of the disease, the most common symptoms were fever (85.65%) and cough (61.24%). The CT features of COVID-19 included pulmonary, bronchial, and pleural changes, with the significant pulmonary presentation of ground-glass opacification (93.30%), consolidation (48.80%), ground-glass opacification plus a reticular pattern (54.07%), telangiectasia (84.21%), and pulmonary fibrotic streaks (49.76%). Spearman analysis showed that the CT findings had significantly inverse associations with the platelets, lymphocyte counts, and sodium levels, but were positively related to the age, erythrocyte sedimentation rate, D-dimer, lactic dehydrogenase, α-hydroxybutyrate dehydrogenase, and C-reactive protein levels (P < .05). In conclusion, the severity of lung abnormalities on CT in COVID-19 patients is inversely associated with the platelets, lymphocyte count, and sodium levels, whereas positively with the age, erythrocyte sedimentation rate, D-dimer, lactic dehydrogenase, hydroxybutyrate dehydrogenase, and C-reactive protein levels.
 
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