Tonka
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http://www.aftonbladet.se/senastenytt/ttnyheter/inrikes/article14055707.ab
Swedish to English translation
Published: 2011-12-09
Medicine against antibiotic resistance:tiphat:
MALMO. Danish researchers say they now have come up with a drug that can make resistant bacteria sensitive to antibiotics again.
They hope that the medicine should be on pharmacy shelves for one to two years.
Scientists have used an old drug for schizophrenia and cleared away the content that affects the brain. It has proved effective in people with drug-resistant tuberculosis in Argentina.
Medicine, as researchers, dubbed JEK47, works by affecting the resistant bacteria's outer cell membrane and prevent the so-called efflux pumps to function. Normally the pump out the antibiotics given and may not get a chance to work.
According to Oliver Hendricks, one of the researchers, the drug proved effective against drug-resistant tuberculosis, multidrug-resistant staphylococci and resistant salmonella.
- It has long been known that schizophrenia-medication also had an antibacterial effect, says Oliver Hendricks said.
- We have simply taken such preparation, and excluding it from the content that affects the brain. The result is a product that can make resistant bacteria sensitive to antibiotics again.
JEK47 is now, according to Hendricks, approved for combination therapy against resistant bacteria in Europe.
Swedish to English translation
Published: 2011-12-09
Medicine against antibiotic resistance:tiphat:
MALMO. Danish researchers say they now have come up with a drug that can make resistant bacteria sensitive to antibiotics again.
They hope that the medicine should be on pharmacy shelves for one to two years.
Scientists have used an old drug for schizophrenia and cleared away the content that affects the brain. It has proved effective in people with drug-resistant tuberculosis in Argentina.
Medicine, as researchers, dubbed JEK47, works by affecting the resistant bacteria's outer cell membrane and prevent the so-called efflux pumps to function. Normally the pump out the antibiotics given and may not get a chance to work.
According to Oliver Hendricks, one of the researchers, the drug proved effective against drug-resistant tuberculosis, multidrug-resistant staphylococci and resistant salmonella.
- It has long been known that schizophrenia-medication also had an antibacterial effect, says Oliver Hendricks said.
- We have simply taken such preparation, and excluding it from the content that affects the brain. The result is a product that can make resistant bacteria sensitive to antibiotics again.
JEK47 is now, according to Hendricks, approved for combination therapy against resistant bacteria in Europe.