tetano
Editor, Senior Moderator
Medicina (Kaunas)
. 2022 Apr 8;58(4):523.
doi: 10.3390/medicina58040523.
Peripheral Neuropathy in Patients Recovering from Severe COVID-19: A Case Series
Pietro Balbi[SUP] 1 2 [/SUP], Annamaria Saltalamacchia[SUP] 1 [/SUP], Francesco Lullo[SUP] 1 [/SUP], Salvatore Fuschillo[SUP] 3 [/SUP], Pasquale Ambrosino[SUP] 4 [/SUP], Pasquale Moretta[SUP] 1 [/SUP], Bernardo Lanzillo[SUP] 1 [/SUP], Mauro Maniscalco[SUP] 3 5 [/SUP]
Affiliations
Abstract
Background and Objectives: Neurological manifestations have been reported in a significant proportion of coronavirus disease 2019 (COVID-19) patients. We aimed to evaluate the prevalence and severity of peripheral nervous system (PNS) involvement in a large group of convalescent COVID-19 patients undergoing in-hospital multidisciplinary rehabilitation. Materials and Methods: Convalescent COVID-19 patients admitted to a Pulmonary Rehabilitation Unit were consecutively screened for inclusion within 48 h of discharge from an acute care setting. All included patients underwent electrophysiological examinations. Results: Among 102 enrolled patients (mean age 62.0 years, 82.4% males), PNS electrophysiological alterations were detected in 42.2%. Mononeuropathies exclusively involving the peroneal nerve were observed in 8.8% (n = 9), while multiple mononeuropathies were similarly reported in nine patients (8.8%). A symmetric sensorimotor polyneuropathy was documented in 24.5% of participants (n = 25). A significant difference was found for exercise capacity and pulmonary function in post hoc comparisons between the three study groups. Conclusions: The risk of neuropathy in the convalescent phase of COVID-19 is relevant. This should be considered when planning multidisciplinary rehabilitation strategies.
Keywords: COVID-19; SARS-CoV-2; chronic disease; disability; exercise; neuropathy; occupational medicine; outcome; rehabilitation.
. 2022 Apr 8;58(4):523.
doi: 10.3390/medicina58040523.
Peripheral Neuropathy in Patients Recovering from Severe COVID-19: A Case Series
Pietro Balbi[SUP] 1 2 [/SUP], Annamaria Saltalamacchia[SUP] 1 [/SUP], Francesco Lullo[SUP] 1 [/SUP], Salvatore Fuschillo[SUP] 3 [/SUP], Pasquale Ambrosino[SUP] 4 [/SUP], Pasquale Moretta[SUP] 1 [/SUP], Bernardo Lanzillo[SUP] 1 [/SUP], Mauro Maniscalco[SUP] 3 5 [/SUP]
Affiliations
- PMID: 35454362
- PMCID: PMC9032555
- DOI: 10.3390/medicina58040523
Abstract
Background and Objectives: Neurological manifestations have been reported in a significant proportion of coronavirus disease 2019 (COVID-19) patients. We aimed to evaluate the prevalence and severity of peripheral nervous system (PNS) involvement in a large group of convalescent COVID-19 patients undergoing in-hospital multidisciplinary rehabilitation. Materials and Methods: Convalescent COVID-19 patients admitted to a Pulmonary Rehabilitation Unit were consecutively screened for inclusion within 48 h of discharge from an acute care setting. All included patients underwent electrophysiological examinations. Results: Among 102 enrolled patients (mean age 62.0 years, 82.4% males), PNS electrophysiological alterations were detected in 42.2%. Mononeuropathies exclusively involving the peroneal nerve were observed in 8.8% (n = 9), while multiple mononeuropathies were similarly reported in nine patients (8.8%). A symmetric sensorimotor polyneuropathy was documented in 24.5% of participants (n = 25). A significant difference was found for exercise capacity and pulmonary function in post hoc comparisons between the three study groups. Conclusions: The risk of neuropathy in the convalescent phase of COVID-19 is relevant. This should be considered when planning multidisciplinary rehabilitation strategies.
Keywords: COVID-19; SARS-CoV-2; chronic disease; disability; exercise; neuropathy; occupational medicine; outcome; rehabilitation.