tetano
Editor, Senior Moderator
Med Clin (Engl Ed)
. 2020 Sep 26.
doi: 10.1016/j.medcle.2020.06.013. Online ahead of print.
Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group
Saioa Zalba Marcos[SUP] 1 [/SUP], Mar?a Luisa Antelo[SUP] 2 [/SUP], Arkaitz Galbete[SUP] 3 [/SUP], Maialen Etayo[SUP] 1 [/SUP], Eva Ongay[SUP] 4 [/SUP], Jos? Antonio Garc?a-Erce[SUP] 5 6 7 [/SUP]
Affiliations
Abstract
in English, Spanish
Background: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease.
Material and methods: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution.
Results: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units.
Conclusion: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results.
Keywords: Blood groups ABO; COVID-19; Coronavirus; Risk factors; SARS-CoV-2; Von Willebrand factor.
. 2020 Sep 26.
doi: 10.1016/j.medcle.2020.06.013. Online ahead of print.
Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group
Saioa Zalba Marcos[SUP] 1 [/SUP], Mar?a Luisa Antelo[SUP] 2 [/SUP], Arkaitz Galbete[SUP] 3 [/SUP], Maialen Etayo[SUP] 1 [/SUP], Eva Ongay[SUP] 4 [/SUP], Jos? Antonio Garc?a-Erce[SUP] 5 6 7 [/SUP]
Affiliations
- PMID: 33015369
- PMCID: PMC7519708
- DOI: 10.1016/j.medcle.2020.06.013
Abstract
in English, Spanish
Background: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease.
Material and methods: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution.
Results: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units.
Conclusion: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results.
Keywords: Blood groups ABO; COVID-19; Coronavirus; Risk factors; SARS-CoV-2; Von Willebrand factor.