Shiloh
Editor, Senior Moderator
Source: http://7thspace.com/headlines/31927...ion_of_genotype_h1_viruses_in_china_2005.html
Measles Resurgence Associated with Continued Circulation of Genotype H1 Viruses in China, 2005
Measles morbidity and mortality decreased significantly after measles vaccine was introduced into China in 1965. From 1995 to 2004, average annual measles incidence decreased to 5.6 cases per 100,000 population following the establishment of a national two-dose regimen.
Molecular characterization of wild-type measles viruses in China during1995-2004 demonstrated that genotype H1 was endemic and widely distributed throughout the country. Surveillance from the National Notifiable Diseases Reporting System (NNDRS) and Chinese Measles Laboratory Network (LabNet) detected a total of 124,865 cases and 55 deaths were in 2005 and this represented a 69.05% increase compared with 2004.
Measles IgM test was detected 81% of 16,017 serum samples obtained from 914 outbreaks.. 213 wild-type measles viruses were isolated from 18 of 31 provinces in China during 2005, and all the isolates belonged to genotype H1.
The ranges of the nucleotide sequence and predicted amino acid sequence homologies of the 213 genotype H1 strains were 93.4%-100% and 90.0%-100%, respectively. H1-associated cases and outbreaks caused the measles resurgence in 2005 in China.
H1 genotype has the most inner variation. It could be divided into 2 clusters, and cluster 1 viruses were predominant in China throughout 2005.
Author: Yixin JiYan ZhangSongtao XuZhen ZhuShuyan ZuoXiaohong JiangPeishan LuChangyin WangYong LiangHuanying ZhengYang LiuNaiying MaoXiaofeng LiangDavid FeatherstonePaul RotaWilliam BelliniWenbo Xu
Credits/Source: Virology Journal 2009, 6:135
Measles Resurgence Associated with Continued Circulation of Genotype H1 Viruses in China, 2005
Measles morbidity and mortality decreased significantly after measles vaccine was introduced into China in 1965. From 1995 to 2004, average annual measles incidence decreased to 5.6 cases per 100,000 population following the establishment of a national two-dose regimen.
Molecular characterization of wild-type measles viruses in China during1995-2004 demonstrated that genotype H1 was endemic and widely distributed throughout the country. Surveillance from the National Notifiable Diseases Reporting System (NNDRS) and Chinese Measles Laboratory Network (LabNet) detected a total of 124,865 cases and 55 deaths were in 2005 and this represented a 69.05% increase compared with 2004.
Measles IgM test was detected 81% of 16,017 serum samples obtained from 914 outbreaks.. 213 wild-type measles viruses were isolated from 18 of 31 provinces in China during 2005, and all the isolates belonged to genotype H1.
The ranges of the nucleotide sequence and predicted amino acid sequence homologies of the 213 genotype H1 strains were 93.4%-100% and 90.0%-100%, respectively. H1-associated cases and outbreaks caused the measles resurgence in 2005 in China.
H1 genotype has the most inner variation. It could be divided into 2 clusters, and cluster 1 viruses were predominant in China throughout 2005.
Author: Yixin JiYan ZhangSongtao XuZhen ZhuShuyan ZuoXiaohong JiangPeishan LuChangyin WangYong LiangHuanying ZhengYang LiuNaiying MaoXiaofeng LiangDavid FeatherstonePaul RotaWilliam BelliniWenbo Xu
Credits/Source: Virology Journal 2009, 6:135