Re: Malaysia Suspt'd Meningitis 450 Quarantined
Re: Malaysia Suspt'd Meningitis 450 Quarantined
Please note news source.
http://www.bernama.com.my/bernama/state_news/news.php?id=410143&cat=ct
Central Region News
(excluding Federal Territory)
May 10, 2009 22:32 PM
Diplococci Bacteria Causing Meningitis In Melaka
MELAKA, May 10 (Bernama) -- The Health Ministry has identified the diplococci bacteria to have caused meningitis to trainees of the Road Transport Department (JPJ) Academy in Tiang Dua, here, resulting in one death last week.
Its minister Datuk Seri Liow Tiong Lai said that until 2pm today, 20 trainees were warded at Melaka Hospital, comprising two at its intensive-care unit and 18 at the isolation ward.
He said six new patients were warded at the same hospital yesterday evening and one today.
"However, we believe the bacterial infection can be controlled with the preventive and rehabilitative measures taken by Melaka Hospital," he said after visiting the patients at the hospital, here, today.
Also present was Melaka Health director Dr Ghazali Othman.
Liow said the 93 JPJ Academy trainees quarantined were being closely observed by a seven-member special task force headed by a doctor for immediate measures to be taken in an emergency.
He said the trainees quarantined had been given ciprofloxacin, an antibiotic while those being treated at the hospital were given ceftnaxone to recover from the infection.
"I saw that the patients at the ICU and isolation ward were okay. The antibiotics given seemed to be working and they (patients) would need seven days of treatment before the next step."
He said residents, especially in Tiang Dua, should not panic over the meningitis situation as the infection could only be spread by droplets when the carrier coughed or sneezed within a one-metre range.
"The meningitis bacteria will not cause an uncontrollable epidemic," he assured.
Liow said samples of the diplococci bacteria had been sent to the microbiology laboratory in Sungai Buloh to ascertain the type as the bacteria had different strains.
"We are also investigating the source of the bacteria by obtaining samples from where the trainees had their practical training, namely in Pedas (Negeri Sembilan), Muar (Johor) and Bukit Katil (Melaka)."
He said all trainees and staff of the JPJ Academy in Tiang Dua were given antibiotics to control the spread of the meningitis bacterial infection.
"I also hope that the public do not speculate on the meningitis infection which has no connection with the influenza A(H1N1) pandemic," he added.
-- BERNAMA
Everything Wikipedia has on the bacterium
http://en.wikipedia.org/wiki/Diplococci
Diplococcus
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A diplococcus (plural diplococci) is a round bacterium (a coccus) that typically occurs in pairs of two joined cells. Examples are Streptococcus pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae and Neisseria meningitidis.
Its name comes from diplo, meaning double, and coccus, meaning berry. This is because berries are round, like a diplococcus, and diplococci come in pairs of two.
In former times, a bacterial genus Diplococcus was recognized, but it is not used anymore.
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Microbiology: Bacteria
Pathogenic bacteria
Bacterial disease · Coley's Toxins · Exotoxin · Lysogenic cycle
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Substrate preference
Lipophilic · Saccharophilic
Oxygen preference
Aerobic (Obligate) · Anaerobic (Facultative, Obligate) · Microaerophile · Nanaerobe · Aerotolerant
Structures
Cell envelope
Cell membrane
Cell wall: Peptidoglycan (NAM, NAG, DAP)
Gram-positive bacteria only: Teichoic acid · Lipoteichoic acid · Endospore
Gram-negative bacteria only: Bacterial outer membrane (Porin, Lipopolysaccharide) · Periplasmic space
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Bacterial cellular morphologies · Coccus (Diplococcus) · Bacillus · Coccobacillus
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http://en.wikipedia.org/wiki/Ciprofloxacin
Ciprofloxacin
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"Cipro" redirects here. For the Rome Metro station, see Cipro (Rome Metro).
Ciprofloxacin
Systematic (IUPAC) name
1-cyclopropyl- 6-fluoro- 4-oxo- 7-piperazin- 1-yl- quinoline- 3-carboxylic acid
Identifiers
CAS number 85721-33-1
......cont..
Metabolism Hepatic, including CYP1A2
Half life 4 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.
B3(AU) C(US)
Legal status
Prescription Only (S4)(AU) POM(UK)
Routes Oral, intravenous, topical (ear drops, eye drops)
Ciprofloxacin (INN) is a synthetic chemotherapeutic agent used to treat severe and life threatening bacterial infections. Ciprofloxacin is commonly referred to as a fluoroquinolone (or quinolone) drug and is a member of the fluoroquinolone class of antibacterials. Ciprofloxacin is marketed worldwide; with well over three hundred different brand names. Ciprofloxacin is marketed in the United States, Canada and the UK as: Ciloxan, Cipro, Cipro XR, Cipro XL Ciproxin and most recently, Proquin (Synonyms: Ciprofloxacin Hydrochloride). In Mexico it is available over the counter and marketed under the names Ciproflox or Ciprofloxacino. Additionally Ciprofloxacin is available as a generic drug under a variety of different brand names and is also available for limited use in veterinary medicine.
Ciprofloxacin was first patented in 1983 by Bayer A.G. and subsequently approved by the United States Food and Drug Administration (FDA) in 1987 to treat severe and life threatening bacterial infections.
The licensed uses for ciprofloxacin in the United States are quite limited as
ciprofloxacin is to be considered a drug of last resort when all other antibiotics have failed. These consist of ten approved uses in the adult population and two approved uses in the pediatric population, as well as a variety of veterinary uses (as documented within the package inserts). Any other use is to be considered off label since it has not been approved by the FDA. Ciprofloxacin interacts with a number of other drugs, a number of herbal and natural supplements, and certain thyroid medications.[2]