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(Major) Improvement of SARS‐CoV‐2 symptoms following Guselkumab injection in a psoriatic patient

Emily

Editor, Senior Moderator
https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.16590
Benhadou, F. and del Marmol, V. (2020), Improvement of SARS‐CoV‐2 symptoms following Guselkumab injection in a psoriatic patient. J Eur Acad Dermatol Venereol, 34: e363-e364. doi:10.1111/jdv.16590
...

We describe the case of a 40‐year‐old lady suffering from psoriasis since 2000. She is treated by guselkumab since January 2019 with complete clearance of her psoriasis. She was previously treated by conventional systemic treatments for psoriasis including methotrexate and cyclosporine. She is also suffering from Ehlers–Danlos syndrome but has no other comorbidity. On 3rd March, she was in contact with her sister and nephews who were all infected by SARS‐CoV‐2. On 9th March, she presented symptoms of SARS‐CoV‐2 infection with severe cough associated to myalgia, fatigue and fever (39.4?C). She reported a rapid worsening of her respiratory symptoms with shortness of breath and despite the use of paracetamol, the fever did not decrease. She administered her guselkumab injection scheduled for March 16. Surprisingly, the day after the injection, she reported a major improvement of her respiratory condition, a normalization of her body temperature and a progressive relief of myalgia and fatigue symptoms....
 
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