Mary Wilson
Well-known member
Published: April 14, 2021
DOI:https://doi.org/10.1016/S1473-3099(21)00205-X
Mattia Trunfio, Andrea Calcagno, Stefano Bonora, Giovanni Di Perri
We read with interest the Personal View by Matthew A Spinelli and colleagues.
[SUP]1[/SUP] We agree with the authors on the evident advantage provided by non-pharmaceutical interventions (facial masking, social distancing, and improved ventilation) in lowering SARS-CoV-2 inoculum, thereby reducing viral transmission. Nevertheless, we call for caution before asserting that such measures could make a substantial difference in reducing COVID-19 severity.
Animal models examining a potential dose?response relationship reported conflicting results, and experimental inoculation might inaccurately mimic real-life infection dynamics,
[SUP]2[/SUP] including inoculum doses. ...
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00205-X/fulltext
DOI:https://doi.org/10.1016/S1473-3099(21)00205-X
Mattia Trunfio, Andrea Calcagno, Stefano Bonora, Giovanni Di Perri
We read with interest the Personal View by Matthew A Spinelli and colleagues.
[SUP]1[/SUP] We agree with the authors on the evident advantage provided by non-pharmaceutical interventions (facial masking, social distancing, and improved ventilation) in lowering SARS-CoV-2 inoculum, thereby reducing viral transmission. Nevertheless, we call for caution before asserting that such measures could make a substantial difference in reducing COVID-19 severity.
Animal models examining a potential dose?response relationship reported conflicting results, and experimental inoculation might inaccurately mimic real-life infection dynamics,
[SUP]2[/SUP] including inoculum doses. ...
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00205-X/fulltext