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Low titers of measles antibody in mothers whose infants suffered from measles before eligible age for measles vaccination

Shiloh

Editor, Senior Moderator
Source: http://7thspace.com/headlines/34355...ore_eligible_age_for_measles_vaccination.html

Low titers of measles antibody in mothers whose infants suffered from measles before eligible age for measles vaccination


Resurgence or outbreak of measles recently occurred in both developed and developing countries despite long-standing widespread use of measles vaccine. Measles incidence in China has increased since 2002, particularly in infants and in persons [greater than or equal to]15 years of age.

It is speculated that infants may acquire fewer measles IgG from their mothers, resulting in the reduced duration of protection during their early months of life. This study aimed to clarify the reason of increased susceptibility to measles in young infants in China...

...Conclusions: Our results suggest that infants born to mothers who acquired immunity to measles by vaccination may get a relatively small amount of measles antibody, resulting in loss of the immunity to measles before the vaccination age.

Measures to improve the immunity in young infants not eligible for measles vaccination would be critical to interrupt the measles transmission in China.

Author: Hong ZhaoPei-Shan LuYali HuQiaozhen WuWenhu YaoYi-Hua Zhou
Credits/Source: Virology Journal 2010, 7:87
 
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