tetano
Editor, Senior Moderator
Virol J. 2011 Jun 9;8(1):288. [Epub ahead of print]
Longitudinal molecular microbial analysis of influenza-like illness in New York City, May 2009 through May 2010.
Tokarz R, Kapoor V, Wu W, Lurio J, Jain K, Mostashari F, Briese T, Lipkin WI.
Abstract
ABSTRACT:
BACKGROUND:
We performed a longitudinal study of viral etiology in samples collected in New York City during May 2009 to May 2010 from outpatients with fever or respiratory disease symptoms in the context of a pilot respiratory virus surveillance system.
METHODS:
Samples were assessed for the presence of 13 viruses, including influenza A virus, by MassTag PCR.
RESULTS:
At least one virus was detected in 52% of 940 samples analyzed, with 3% showing co-infections. The most frequently detected agents were rhinoviruses and influenza A, all representing the 2009 pandemic H1N1 strain. The incidence of influenza H1N1-positive samples was highest in late spring 2009, followed by a decline in summer and early fall, when rhinovirus infections became predominant before H1N1 reemerged in winter. Our study also identified a focal outbreak of enterovirus 68 in the early fall of 2009.
CONCLUSION:
MassTag multiplex PCR affords opportunities to track the epidemiology of infectious diseases and may guide clinicians and public health practitioners in influenza-like illness and outbreak management. Nonetheless, a substantial proportion of influenza-like illness remains unexplained underscoring the need for additional platforms.
PMID:
21658237
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21658237
Longitudinal molecular microbial analysis of influenza-like illness in New York City, May 2009 through May 2010.
Tokarz R, Kapoor V, Wu W, Lurio J, Jain K, Mostashari F, Briese T, Lipkin WI.
Abstract
ABSTRACT:
BACKGROUND:
We performed a longitudinal study of viral etiology in samples collected in New York City during May 2009 to May 2010 from outpatients with fever or respiratory disease symptoms in the context of a pilot respiratory virus surveillance system.
METHODS:
Samples were assessed for the presence of 13 viruses, including influenza A virus, by MassTag PCR.
RESULTS:
At least one virus was detected in 52% of 940 samples analyzed, with 3% showing co-infections. The most frequently detected agents were rhinoviruses and influenza A, all representing the 2009 pandemic H1N1 strain. The incidence of influenza H1N1-positive samples was highest in late spring 2009, followed by a decline in summer and early fall, when rhinovirus infections became predominant before H1N1 reemerged in winter. Our study also identified a focal outbreak of enterovirus 68 in the early fall of 2009.
CONCLUSION:
MassTag multiplex PCR affords opportunities to track the epidemiology of infectious diseases and may guide clinicians and public health practitioners in influenza-like illness and outbreak management. Nonetheless, a substantial proportion of influenza-like illness remains unexplained underscoring the need for additional platforms.
PMID:
21658237
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21658237