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Long-term Cell Phone Use Linked to Malignant Brain Tumor Risk

Emily

Editor, Senior Moderator
http://www.medscape.com/viewarticle/834888
Long-term Cell Phone Use Linked to Brain Tumor Risk

Pauline Anderson
November 13, 2014
Long-term use of both mobile and cordless phones is associated with an increased risk for glioma, the most common type of brain tumor, the latest research on the subject concludes.

The new study shows that the risk for glioma was tripled among those using a wireless phone for more than 25 years and that the risk was also greater for those who had started using mobile or cordless phones before age 20 years.

"Doctors should be very concerned by this and discuss precautions with their patients," study author Lennart Hardell, MD, PhD, professor, Department of Oncology, University Hospital, ?rebro, Sweden, told Medscape Medical News...
 
Re: Long-term Cell Phone Use Linked to Malignant Brain Tumor Risk

Mobile phone and cordless phone use and the risk for glioma ? Analysis of pooled case-control studies in Sweden, 1997?2003 and 2007?2009

Hardell, Lennart et al.
Pathophysiology

Abstract

We made a pooled analysis of two case-control studies on malignant brain tumours with patients diagnosed during 1997?2003 and 2007?2009. They were aged 20?80 years and 18?75 years, respectively, at the time of diagnosis. Only cases with histopathological verification of the tumour were included. Population-based controls, matched on age and gender, were used. Exposures were assessed by questionnaire. The whole reference group was used in the unconditional regression analysis adjusted for gender, age, year of diagnosis, and socio-economic index. In total, 1498 (89%) cases and 3530 (87%) controls participated. Mobile phone use increased the risk of glioma, OR = 1.3, 95% CI = 1.1?1.6 overall, increasing to OR = 3.0, 95% CI = 1.7?5.2 in the >25 year latency group. Use of cordless phones increased the risk to OR = 1.4, 95% CI = 1.1?1.7, with highest risk in the >15?20 years latency group yielding OR = 1.7, 95% CI = 1.1?2.5. The OR increased statistically significant both per 100 h of cumulative use, and per year of latency for mobile and cordless phone use. Highest ORs overall were found for ipsilateral mobile or cordless phone use, OR = 1.8, 95% CI = 1.4?2.2 and OR = 1.7, 95% CI = 1.3?2.1, respectively. The highest risk was found for glioma in the temporal lobe. First use of mobile or cordless phone before the age of 20 gave higher OR for glioma than in later age groups.

full text available at: http://www.pathophysiologyjournal.com/article/S0928-4680(14)00064-9/fulltext
 
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