tetano
Editor, Senior Moderator
J Mol Cell Biol. 2011 Mar 23. [Epub ahead of print]
Learning from the 2009 H1N1 pandemic: prospects for more broadly effective influenza vaccines.
Settembre EC, Dormitzer PR, Rappuoli R.
Novartis Vaccines and Diagnostics, Cambridge, MA, USA, and Siena, Italy.
Abstract
Calls to develop a universal influenza vaccine have increased in the wake of the 2009 H1N1 influenza pandemic. This demand comes at a time when analyses of the human antibody repertoire, informed by structures of complexes between broadly neutralizing antibodies and influenza hemagglutinin, have revealed the target of a class of broadly neutralizing antibodies. Recent studies suggest a path forward to more broadly protective influenza vaccines.
PMID: 21430014 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21430014
Learning from the 2009 H1N1 pandemic: prospects for more broadly effective influenza vaccines.
Settembre EC, Dormitzer PR, Rappuoli R.
Novartis Vaccines and Diagnostics, Cambridge, MA, USA, and Siena, Italy.
Abstract
Calls to develop a universal influenza vaccine have increased in the wake of the 2009 H1N1 influenza pandemic. This demand comes at a time when analyses of the human antibody repertoire, informed by structures of complexes between broadly neutralizing antibodies and influenza hemagglutinin, have revealed the target of a class of broadly neutralizing antibodies. Recent studies suggest a path forward to more broadly protective influenza vaccines.
PMID: 21430014 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21430014