tetano
Editor, Senior Moderator
Kidney Res Clin Pract
. 2024 May 29.
doi: 10.23876/j.krcp.23.287. Online ahead of print. Comparative analysis of the incidence and mortality of COVID-19 in Korean end-stage kidney disease patients: hemodialysis, peritoneal dialysis, and transplantation
AJin Cho[SUP] 1 2 [/SUP], Seon A Jeong[SUP] 3 [/SUP], Hayne Cho Park[SUP] 1 2 [/SUP], Do Hyoung Kim[SUP] 1 2 [/SUP], Kyung Don Yoo[SUP] 4 [/SUP], Hye Eun Yoon[SUP] 5 [/SUP], Yang Gyun Kim[SUP] 6 [/SUP], Young-Ki Lee[SUP] 1 2 [/SUP]; Korean Society of Nephrology Disaster Preparedness and Response Committee
Affiliations
Background: Patients with end-stage kidney disease (ESKD) are more susceptible to viral epidemics and are known to have higher incidence and death rates of coronavirus disease 2019 (COVID-19) compared to the general population. We determined COVID-19 incidence and mortality among chronic hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) patients in Korea.
Methods: We conducted a retrospective cohort study and data regarding Korean ESKD adults (aged ≥18 years) were obtained from the National Health Insurance Service of Korea from October 2020 to December 2021. We examined and compared the incidence of COVID-19-related infections and deaths among the patients receiving HD, PD, and KT.
Results: Of all ESKD patients, 85,018 (68.1%) were on HD, 8,399 (6.7%) on PD, and 31,343 (25.1%) on KT. The COVID-19 incidence was 1.3% for HD, 1.2% for PD, and 1.5% for KT. COVID-19 mortality was 16.3% for HD, 12.2% for PD, and 4.7% for KT. PD patients had a lower incidence of infection compared to HD patients (odds ratio [OR], 0.76; 95% confidence interval [CI], 0.607-0.93), but KT patients had a significantly higher risk of infection (OR, 1.28; 95% CI, 1.13-1.44). Compared with HD, the risk of COVID-19-related death was not different for PD patients but was significantly lower for KT patients (hazard ratio, 0.55; 95% CI, 0.35-0.88).
Conclusion: COVID-19 incidence was lower in PD patients than in HD patients, but mortality was not different between them. KT was associated with a higher risk of COVID-19 infection but lower mortality compared to HD.
Keywords: COVID-19; Kidney transplantation; Mortality; Peritoneal dialysis; Renal dialysis.
. 2024 May 29.
doi: 10.23876/j.krcp.23.287. Online ahead of print. Comparative analysis of the incidence and mortality of COVID-19 in Korean end-stage kidney disease patients: hemodialysis, peritoneal dialysis, and transplantation
AJin Cho[SUP] 1 2 [/SUP], Seon A Jeong[SUP] 3 [/SUP], Hayne Cho Park[SUP] 1 2 [/SUP], Do Hyoung Kim[SUP] 1 2 [/SUP], Kyung Don Yoo[SUP] 4 [/SUP], Hye Eun Yoon[SUP] 5 [/SUP], Yang Gyun Kim[SUP] 6 [/SUP], Young-Ki Lee[SUP] 1 2 [/SUP]; Korean Society of Nephrology Disaster Preparedness and Response Committee
Affiliations
- PMID: 38934044
- DOI: 10.23876/j.krcp.23.287
Background: Patients with end-stage kidney disease (ESKD) are more susceptible to viral epidemics and are known to have higher incidence and death rates of coronavirus disease 2019 (COVID-19) compared to the general population. We determined COVID-19 incidence and mortality among chronic hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) patients in Korea.
Methods: We conducted a retrospective cohort study and data regarding Korean ESKD adults (aged ≥18 years) were obtained from the National Health Insurance Service of Korea from October 2020 to December 2021. We examined and compared the incidence of COVID-19-related infections and deaths among the patients receiving HD, PD, and KT.
Results: Of all ESKD patients, 85,018 (68.1%) were on HD, 8,399 (6.7%) on PD, and 31,343 (25.1%) on KT. The COVID-19 incidence was 1.3% for HD, 1.2% for PD, and 1.5% for KT. COVID-19 mortality was 16.3% for HD, 12.2% for PD, and 4.7% for KT. PD patients had a lower incidence of infection compared to HD patients (odds ratio [OR], 0.76; 95% confidence interval [CI], 0.607-0.93), but KT patients had a significantly higher risk of infection (OR, 1.28; 95% CI, 1.13-1.44). Compared with HD, the risk of COVID-19-related death was not different for PD patients but was significantly lower for KT patients (hazard ratio, 0.55; 95% CI, 0.35-0.88).
Conclusion: COVID-19 incidence was lower in PD patients than in HD patients, but mortality was not different between them. KT was associated with a higher risk of COVID-19 infection but lower mortality compared to HD.
Keywords: COVID-19; Kidney transplantation; Mortality; Peritoneal dialysis; Renal dialysis.