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Jpn J Infect Dis . A family case of COVID-19 pneumonia with different chest CT features and duration of SARS-CoV-2 shedding: a case report from Japa

tetano

Editor, Senior Moderator
Jpn J Infect Dis


. 2021 Mar 31.
doi: 10.7883/yoken.JJID.2021.019. Online ahead of print.
A family case of COVID-19 pneumonia with different chest CT features and duration of SARS-CoV-2 shedding: a case report from Japan


Shigeki Ochiai[SUP] 1 2 [/SUP], Yuichi Kama[SUP] 1 2 [/SUP], Kota Hirai[SUP] 1 2 [/SUP], Hidetoshi Yano[SUP] 1 2 [/SUP], Ayumi Tada[SUP] 2 [/SUP], Chinami Kaiga[SUP] 1 2 [/SUP], Takashi Sakama[SUP] 1 2 [/SUP], Hiromitsu Takakura[SUP] 1 2 [/SUP], Koichi Yamaguchi[SUP] 1 2 [/SUP], Hiroyuki Mochizuki[SUP] 1 [/SUP], Masahiko Kato[SUP] 1 2 [/SUP]



Affiliations

Abstract

Coronavirus disease 2019 (COVID-19) pneumonia in children characteristically has a milder clinical presentation, with milder inflammatory biomarkers and radiological findings. Accumulating evidence indicates a difference in chest computed tomography (CT) features and duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding between children and adults. Here, we report a family case of COVID-19 pneumonia in which two brothers (age 14 years and 2 years) had different findings. On admission, the 2-year-old had few symptoms with no sign of pneumonia, whereas the older brother had presented with pneumonia on admission. Both were positive for SARS-CoV-2 infection on polymerase chain reaction. They both had obvious characteristic signs of COVID-19 pneumonia on chest CT. However, CT findings in the younger brother were non-specific and similar to other pneumonias. The older brother required longer treatment because of a longer shedding period of SARS-CoV-2 detected in nasopharyngeal samples. Both boys were discharged without complications. This family case suggests that the clinical features of COVID-19 pneumonia might differ between younger and older children.

Keywords: COVID-19; CT scan; children; opacity; radiography.
 
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