Japan - Ministry of Health, Labor and Welfare statement: 2 possible cases of acute hepatitis of unknown cause in a child - April 25, 2022+

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Posted on Monday, April 25, 2022

[FONT=ヒラギノ角ゴ Pro W3]About acute hepatitis of unknown cause in children[/FONT]



[FONT=ヒラギノ角ゴ Pro W3]　As of April 21, World Health Organization (WHO) reports continue to report acute hepatitis of unknown etiology in at least 169 children (1 death) in 12 countries. Of these, adenovirus was detected in 74 cases, but it is said that the causative virus is unknown. It is also unclear whether acute hepatitis is actually increasing in children. WHO has established a provisional case definition for the purpose of identifying the cause of this acute hepatitis, and is requesting each country to report cases that fall under the case definition.
　On April 20, 1945, the Ministry of Health, Labor and Welfare has issued an administrative contact to local governments, etc. regarding such cases, calling attention and requesting information provision.
　We have recently received a notification that one inpatient case corresponding to 2 "possible cases" of the provisional case definition (*) created by WHO has occurred, so we will announce it as attached. In the future, we will regularly compile and publish the status of case reports.
　The Ministry of Health, Labor and Welfare will continue to cooperate with the governments of each country, WHO, experts, etc., and strive to collect information while paying close attention to the infection situation in other countries.
　Please be considerate of the protection of personal information so that the person or family member is not identified by the media.

* WHO has established the following provisional working case definition on April 23.
1 Confirmed: None at this time. 2 Probable: Aspartate transaminase (AST) or alanine transaminase (ALT) presents with acute hepatitis (excluding hepatitis A to E [SUP]*[/SUP]
) exceeding 500 IU / L after January 1, 2021. Children under 16 years
3 Epi-linked cases: Acute hepatitis (excluding hepatitis A to E) of any age who is a close contact of confirmed cases (before April 22) after January 1, 2021 [SUP]*[/SUP] )
* If the result of hepatitis virus AE meets the above definition, it can be reported as "waiting for classification".[/FONT]

https://www.mhlw.go.jp/stf/newpage_25423.html

 

[sharon sanders]

Please see:

W.H.O. - Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland - April 15, 2022

U.S., U.K. investigating unusual cases of hepatitis in young children - April 15, 2022

US - Alabama: Investigations of nine young children with adenovirus are underway - April 15, 2022

Investigation into cases of hepatitis of unknown aetiology among young children, Scotland. 1 January 2022 to 12 April 2022 - Eurosurveillance - April 15, 2022

Hepatitis cases of unknown cause being investigated among Irish children - April 15, 2022

Mystery outbreak of hepatitis in children investigated in the UK - April 11, 2022

 

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[sharon sanders]

2nd possible case discovered

[FONT=ヒラギノ角ゴ Pro W3]About acute hepatitis of unknown cause in children (April 28, 4th year of Reiwa)[/FONT]



[FONT=ヒラギノ角ゴ Pro W3]　As of April 21, World Health Organization (WHO) reports continue to report unexplained acute hepatitis in at least 169 children (1 death) in 12 countries. Of these, adenovirus was detected in 74 cases, but it is said that the causative virus is unknown. It is also unclear whether acute hepatitis is actually increasing in children. WHO has established a provisional case definition for the purpose of identifying the cause of this acute hepatitis, and is requesting each country to report cases that fall under the case definition.
　Regarding these cases, the Ministry of Health, Labor and Welfare issued a warning and request for information to local governments, etc. on April 20, 1945, and on April 27, issued an administrative contact regarding the infectious disease surveillance and active epidemiological investigation of the case. I'm putting it out.
　The cumulative number of reported cases from October 1, 2021 to April 28, 2022, which corresponds to 2 "Possible cases" in the provisional case definition (*), will be announced as attached. We will continue to regularly compile and publish the status of case reports.
　The Ministry of Health, Labor and Welfare will continue to cooperate with the governments of each country, WHO, experts, etc., and strive to collect information while paying close attention to the infection situation in other countries.
Please be considerate of the protection of personal information so that the person or family member is not identified by the media.


* The definition of provisional cases is as follows. "Acute hepatitis of unknown cause in children in Europe and the United States (cooperation request)" (Ministry of Health, Labor and Welfare, Ministry of Health, Labor and Welfare, Tuberculosis Infectious Diseases Division, Office Contact)
Diagnosed after October 1, 2021 Among hospitalized cases with unexplained hepatitis, those who meet any of the following 1, 2, and 3:
1 Confirmed cases None at this time.
2 Possible examples Among children under 16 years of age who presented with acute hepatitis with aspartate transaminase (AST) or alanine transaminase (ALT) exceeding 500 IU / L, those who were denied the involvement of hepatitis A to E virus. ..
3 Among those who present acute hepatitis of any age who are close contacts of epidemiologically related cases 2, those who have been denied the involvement of hepatitis A to E viruses.[/FONT]

• [FONT=ヒラギノ角ゴ Pro W3]About acute hepatitis of unknown cause in children (press release on April 28, 4th year of Reiwa)[/FONT]

 

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