tetano
Editor, Senior Moderator
JACC Case Rep
. 2021 Feb 24.
doi: 10.1016/j.jaccas.2020.11.045. Online ahead of print.
Reversible Coronary Artery Aneurysm With Delayed Anti-inflammatory Therapy in Multisystem Inflammatory Syndrome in Children
Ramzi Shaykh[SUP] 1 [/SUP], Shoshana Leftin[SUP] 1 [/SUP], Sanghee Suh[SUP] 1 2 [/SUP], Robert Spencer[SUP] 1 2 [/SUP], Mark Gorelik[SUP] 2 3 [/SUP], Patrick T Wilson[SUP] 2 3 [/SUP], Rebekah Diamond[SUP] 2 3 [/SUP]
Affiliations
Abstract
A 4-year-old boy with multisystem inflammatory syndrome in children before widespread recognition of this disease developed complications, including coronary artery aneurysm, without anti-inflammatory treatment. With delayed treatment, all sequelae resolved. This case demonstrates a natural history supporting the role of anti-inflammatory treatment even with delayed or equivocal diagnosis. (Level of Difficulty: Intermediate.).
Keywords: HD, hospital day; KD, Kawasaki disease; LAD, left anterior descending; MIS-C, multisystem inflammatory syndrome in children; NT-proBNP, N-terminal pro–B-type natriuretic peptide; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; autoimmune; coronary vessel anomaly; echocardiography; hemodynamics; shortness of breath; tachycardia.
. 2021 Feb 24.
doi: 10.1016/j.jaccas.2020.11.045. Online ahead of print.
Reversible Coronary Artery Aneurysm With Delayed Anti-inflammatory Therapy in Multisystem Inflammatory Syndrome in Children
Ramzi Shaykh[SUP] 1 [/SUP], Shoshana Leftin[SUP] 1 [/SUP], Sanghee Suh[SUP] 1 2 [/SUP], Robert Spencer[SUP] 1 2 [/SUP], Mark Gorelik[SUP] 2 3 [/SUP], Patrick T Wilson[SUP] 2 3 [/SUP], Rebekah Diamond[SUP] 2 3 [/SUP]
Affiliations
- PMID: 33649746
- PMCID: PMC7904278
- DOI: 10.1016/j.jaccas.2020.11.045
Abstract
A 4-year-old boy with multisystem inflammatory syndrome in children before widespread recognition of this disease developed complications, including coronary artery aneurysm, without anti-inflammatory treatment. With delayed treatment, all sequelae resolved. This case demonstrates a natural history supporting the role of anti-inflammatory treatment even with delayed or equivocal diagnosis. (Level of Difficulty: Intermediate.).
Keywords: HD, hospital day; KD, Kawasaki disease; LAD, left anterior descending; MIS-C, multisystem inflammatory syndrome in children; NT-proBNP, N-terminal pro–B-type natriuretic peptide; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; autoimmune; coronary vessel anomaly; echocardiography; hemodynamics; shortness of breath; tachycardia.