tetano
Editor, Senior Moderator
JACC Adv
. 2022 Aug 10;100057.
doi: 10.1016/j.jacadv.2022.100057. Online ahead of print.
Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections
Joan E Briller[SUP] 1 [/SUP], Niti R Aggarwal[SUP] 2 [/SUP], Melinda B Davis[SUP] 3 [/SUP], Afshan B Hameed[SUP] 4 [/SUP], Isabelle Malhamé[SUP] 5 [/SUP], Zainab Mahmoud[SUP] 6 [/SUP], Emily G McDonald[SUP] 5 [/SUP], Glaucia Moraes de Oliveira[SUP] 7 [/SUP], Odayme Quesada[SUP] 8 9 [/SUP], Nandita S Scott[SUP] 10 11 [/SUP], Jyoti Sharma[SUP] 12 [/SUP], American College of Cardiology Cardiovascular Disease in Women Committee
Affiliations
Abstract
Cardiovascular complications are frequently present in coronavirus 2019 (COVID-19) infection. These include microvascular and macrovascular thrombotic complications such as arterial and venous thromboembolism, myocardial injury or inflammation resulting in infarction, heart failure, and arrhythmias. Data suggest increased risk of adverse outcomes in pregnant compared with nonpregnant women of reproductive age with COVID-19 infection, including need for intensive care unit admission, mechanical ventilation, and extracorporeal membrane oxygenation utilization. Current statements addressing COVID-19-associated cardiac complications do not include pregnancy complications that may mimic COVID-19 complications such as peripartum cardiomyopathy, spontaneous coronary artery dissection, and preeclampsia. Unique to pregnancy, COVID-19 complications can result in preterm delivery and modify management of the pregnancy. Moreover, pregnancy has often been an exclusion criterion for enrollment in research studies. In this review, we summarize what is known about pregnancy-associated COVID-19 cardiovascular complications.
Keywords: CDC, Centers for Disease Control; COVID-19, coronavirus-2019; ECG, electrocardiogram; ECMO, extracorporeal membrane oxygenation; LV, left ventricular; MI, myocardial injury; PASC, postacute sequelae of SARS-CoV-2 infection; PPCM, peripartum cardiomyopathy; SCAD, spontaneous coronary artery dissection; Tn, cardiac troponin; arrhythmias; cardio-obstetrics; peripartum cardiomyopathy; preeclampsia; thromboembolic disease; vaccine induced thrombocytopenia.
. 2022 Aug 10;100057.
doi: 10.1016/j.jacadv.2022.100057. Online ahead of print.
Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections
Joan E Briller[SUP] 1 [/SUP], Niti R Aggarwal[SUP] 2 [/SUP], Melinda B Davis[SUP] 3 [/SUP], Afshan B Hameed[SUP] 4 [/SUP], Isabelle Malhamé[SUP] 5 [/SUP], Zainab Mahmoud[SUP] 6 [/SUP], Emily G McDonald[SUP] 5 [/SUP], Glaucia Moraes de Oliveira[SUP] 7 [/SUP], Odayme Quesada[SUP] 8 9 [/SUP], Nandita S Scott[SUP] 10 11 [/SUP], Jyoti Sharma[SUP] 12 [/SUP], American College of Cardiology Cardiovascular Disease in Women Committee
Affiliations
- PMID: 35967591
- PMCID: PMC9364954
- DOI: 10.1016/j.jacadv.2022.100057
Abstract
Cardiovascular complications are frequently present in coronavirus 2019 (COVID-19) infection. These include microvascular and macrovascular thrombotic complications such as arterial and venous thromboembolism, myocardial injury or inflammation resulting in infarction, heart failure, and arrhythmias. Data suggest increased risk of adverse outcomes in pregnant compared with nonpregnant women of reproductive age with COVID-19 infection, including need for intensive care unit admission, mechanical ventilation, and extracorporeal membrane oxygenation utilization. Current statements addressing COVID-19-associated cardiac complications do not include pregnancy complications that may mimic COVID-19 complications such as peripartum cardiomyopathy, spontaneous coronary artery dissection, and preeclampsia. Unique to pregnancy, COVID-19 complications can result in preterm delivery and modify management of the pregnancy. Moreover, pregnancy has often been an exclusion criterion for enrollment in research studies. In this review, we summarize what is known about pregnancy-associated COVID-19 cardiovascular complications.
Keywords: CDC, Centers for Disease Control; COVID-19, coronavirus-2019; ECG, electrocardiogram; ECMO, extracorporeal membrane oxygenation; LV, left ventricular; MI, myocardial injury; PASC, postacute sequelae of SARS-CoV-2 infection; PPCM, peripartum cardiomyopathy; SCAD, spontaneous coronary artery dissection; Tn, cardiac troponin; arrhythmias; cardio-obstetrics; peripartum cardiomyopathy; preeclampsia; thromboembolic disease; vaccine induced thrombocytopenia.