tetano
Editor, Senior Moderator
J Xray Sci Technol. 2020 Apr 7. doi: 10.3233/XST-200670. [Epub ahead of print]
Clinical and computed tomographic (CT) images characteristics in the patients with COVID-19 infection: What should radiologists need to know?
Lei P[SUP]1[/SUP], Huang Z[SUP]1[/SUP], Liu G[SUP]1[/SUP], Wang P[SUP]2[/SUP], Song W[SUP]1[/SUP], Mao J[SUP]1[/SUP], Shen G[SUP]1[/SUP], Zhou S[SUP]1[/SUP], Qian W[SUP]3[/SUP], Jiao J[SUP]1[/SUP].
Author information
Abstract
OBJECTIVE:
To evaluate the clinical and computed tomographic (CT) features in the patients with COVID-19 pneumonia confirmed by the real-time reverse transcriptase polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample.
MATERIAL AND METHODS:
Clinical information and CT findings of a total of 14 patients with COVID-19 infection (age range, 12-83 years; females 6) were analyzed retrospectively. The clinical information includes the history of exposure, laboratory results, and the symptoms (such as fever, cough, headache, etc.); CT findings of chest include the extension and distribution of lesion, the ground-glass opacity (GGO), consolidation, bronchovascular enlarged, irregular linear appearances, pleural effusion, and lymphadenopathy.
RESULTS:
Eight patients had the exposure history for recent travel to Wuhan of Hubei province (8/14, 57%), 6 had the exposure to patients with COVID-19 infection. Significant statistical differences were observed in lymphocyte percentage decreased and C-reactive protein elevated (p = 0.015). Seven patients had fever, 7 had cough, 2 had headache, 3 had fatigue, 1 had body soreness, 3 had diarrhea, and 2 had no obvious symptoms. In chest CT examination, 10 patients were positive (10/14, 71.43%). Among these patients, 9 had lesions involving both lungs (9/10, 90%), 8 had lesions involving 4 to 5 lobes (8/10, 80%). Most of lesions were distributed peripherally and the most significant lesions were observed in the right lower lobe in 9 patients (9/10, 90%). Nodules were observed in 5 patients (5/10, 50%); GGO, consolidation, and bronchovascular enlarged were shown in 9 patients (9/10, 90%); irregular linear appearances were revealed in 7 patients (7/10, 70%); and pleural effusions were exhibited in 2 patients (2/10, 20%). Last, no patients showed lymphadenopathy.
CONCLUSION:
There were some typical CT features for diagnosis of COVID-19 pneumonia. The radiologists should know these CT findings and clinical information, which could help for accurate analysis in the patients with 2019 novel coronavirus infection.
KEYWORDS:
COVID-19 infection; Novel coronavirus; computed tomographic findings; virus pneumonia
PMID:32280076DOI:10.3233/XST-200670
Clinical and computed tomographic (CT) images characteristics in the patients with COVID-19 infection: What should radiologists need to know?
Lei P[SUP]1[/SUP], Huang Z[SUP]1[/SUP], Liu G[SUP]1[/SUP], Wang P[SUP]2[/SUP], Song W[SUP]1[/SUP], Mao J[SUP]1[/SUP], Shen G[SUP]1[/SUP], Zhou S[SUP]1[/SUP], Qian W[SUP]3[/SUP], Jiao J[SUP]1[/SUP].
Author information
Abstract
OBJECTIVE:
To evaluate the clinical and computed tomographic (CT) features in the patients with COVID-19 pneumonia confirmed by the real-time reverse transcriptase polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample.
MATERIAL AND METHODS:
Clinical information and CT findings of a total of 14 patients with COVID-19 infection (age range, 12-83 years; females 6) were analyzed retrospectively. The clinical information includes the history of exposure, laboratory results, and the symptoms (such as fever, cough, headache, etc.); CT findings of chest include the extension and distribution of lesion, the ground-glass opacity (GGO), consolidation, bronchovascular enlarged, irregular linear appearances, pleural effusion, and lymphadenopathy.
RESULTS:
Eight patients had the exposure history for recent travel to Wuhan of Hubei province (8/14, 57%), 6 had the exposure to patients with COVID-19 infection. Significant statistical differences were observed in lymphocyte percentage decreased and C-reactive protein elevated (p = 0.015). Seven patients had fever, 7 had cough, 2 had headache, 3 had fatigue, 1 had body soreness, 3 had diarrhea, and 2 had no obvious symptoms. In chest CT examination, 10 patients were positive (10/14, 71.43%). Among these patients, 9 had lesions involving both lungs (9/10, 90%), 8 had lesions involving 4 to 5 lobes (8/10, 80%). Most of lesions were distributed peripherally and the most significant lesions were observed in the right lower lobe in 9 patients (9/10, 90%). Nodules were observed in 5 patients (5/10, 50%); GGO, consolidation, and bronchovascular enlarged were shown in 9 patients (9/10, 90%); irregular linear appearances were revealed in 7 patients (7/10, 70%); and pleural effusions were exhibited in 2 patients (2/10, 20%). Last, no patients showed lymphadenopathy.
CONCLUSION:
There were some typical CT features for diagnosis of COVID-19 pneumonia. The radiologists should know these CT findings and clinical information, which could help for accurate analysis in the patients with 2019 novel coronavirus infection.
KEYWORDS:
COVID-19 infection; Novel coronavirus; computed tomographic findings; virus pneumonia
PMID:32280076DOI:10.3233/XST-200670