tetano
Editor, Senior Moderator
J Ultrasound Med
. 2022 Jan 18.
doi: 10.1002/jum.15944. Online ahead of print.
Early Lung Ultrasound Findings in Patients With COVID-19 Pneumonia: A Retrospective Multicenter Study of 479 Patients
Costantino Caroselli[SUP] 1 [/SUP], Michael Blaivas[SUP] 2 [/SUP], Matteo Marcosignori[SUP] 3 [/SUP], Yale Tung Chen[SUP] 4 [/SUP], Sara Falzetti[SUP] 5 [/SUP], José Mariz[SUP] 6 7 8 9 [/SUP], Romano Fiorentino[SUP] 10 [/SUP], Rafael Pinto Silva[SUP] 11 [/SUP], Joana Gomes Cochicho[SUP] 12 [/SUP], Simone Sebastiani[SUP] 13 [/SUP], Mauro Carlini[SUP] 14 [/SUP], Enrico Polati[SUP] 15 [/SUP], Valentina Simonini[SUP] 16 [/SUP], Sara Malagola[SUP] 17 [/SUP], Irene Raffaldi[SUP] 18 [/SUP], Daniele Longo[SUP] 19 20 [/SUP]
Affiliations
Abstract
Objectives: Lung ultrasound (LUS) holds the promise of an accurate, radiation-free, and affordable diagnostic and monitoring tool in coronavirus disease 2019 (COVID-19) pneumonia. We sought to evaluate the usefulness of LUS in the diagnosis of patients with respiratory distress and suspicion of interstitial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, in comparison to other imaging modalities.
Methods: This was a multicenter, retrospective study. LUS was performed, on Emergency Department (ED) arrival of patients presenting for possible COVID-19 evaluation, by trained emergency physicians, before undergoing conventional radiologic examination or while waiting for the report. Scans were performed using longitudinal transducer orientation of the lung regions. CXR was interpreted by radiologists staffing ED radiology. Subjects were divided into two group based on molecular test results. LUS findings were compared to COVID test results, nonlaboratory data, and other imaging for each patient. Categorical variables were expressed as percentages and continuous variables as median ± standard error.
Results: A total of 479 patients were enrolled, 87% diagnosed with SARS-CoV-2 by molecular testing. COVID positive and COVID negative patients differed with respect to sex, presence of fever, and white blood cells count. Most common findings on lung point of care ultrasound (POCUS) for COVID-positive patients were B-lines, irregular pleural lines, and small consolidation. Normal chest X-ray was found in 17.89% of cases.
Conclusions: This 479 patient cohort, with COVID-19, found LUS to be noninferior to chest X-ray (CXR) for diagnostic accuracy. In this study, COVID-positive patients are most likely to show B lines and sub-pleural consolidations on LUS examination.
Keywords: COVID-19; SARS-CoV-2; lung ultrasound; point-of-care.
. 2022 Jan 18.
doi: 10.1002/jum.15944. Online ahead of print.
Early Lung Ultrasound Findings in Patients With COVID-19 Pneumonia: A Retrospective Multicenter Study of 479 Patients
Costantino Caroselli[SUP] 1 [/SUP], Michael Blaivas[SUP] 2 [/SUP], Matteo Marcosignori[SUP] 3 [/SUP], Yale Tung Chen[SUP] 4 [/SUP], Sara Falzetti[SUP] 5 [/SUP], José Mariz[SUP] 6 7 8 9 [/SUP], Romano Fiorentino[SUP] 10 [/SUP], Rafael Pinto Silva[SUP] 11 [/SUP], Joana Gomes Cochicho[SUP] 12 [/SUP], Simone Sebastiani[SUP] 13 [/SUP], Mauro Carlini[SUP] 14 [/SUP], Enrico Polati[SUP] 15 [/SUP], Valentina Simonini[SUP] 16 [/SUP], Sara Malagola[SUP] 17 [/SUP], Irene Raffaldi[SUP] 18 [/SUP], Daniele Longo[SUP] 19 20 [/SUP]
Affiliations
- PMID: 35040507
- DOI: 10.1002/jum.15944
Abstract
Objectives: Lung ultrasound (LUS) holds the promise of an accurate, radiation-free, and affordable diagnostic and monitoring tool in coronavirus disease 2019 (COVID-19) pneumonia. We sought to evaluate the usefulness of LUS in the diagnosis of patients with respiratory distress and suspicion of interstitial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, in comparison to other imaging modalities.
Methods: This was a multicenter, retrospective study. LUS was performed, on Emergency Department (ED) arrival of patients presenting for possible COVID-19 evaluation, by trained emergency physicians, before undergoing conventional radiologic examination or while waiting for the report. Scans were performed using longitudinal transducer orientation of the lung regions. CXR was interpreted by radiologists staffing ED radiology. Subjects were divided into two group based on molecular test results. LUS findings were compared to COVID test results, nonlaboratory data, and other imaging for each patient. Categorical variables were expressed as percentages and continuous variables as median ± standard error.
Results: A total of 479 patients were enrolled, 87% diagnosed with SARS-CoV-2 by molecular testing. COVID positive and COVID negative patients differed with respect to sex, presence of fever, and white blood cells count. Most common findings on lung point of care ultrasound (POCUS) for COVID-positive patients were B-lines, irregular pleural lines, and small consolidation. Normal chest X-ray was found in 17.89% of cases.
Conclusions: This 479 patient cohort, with COVID-19, found LUS to be noninferior to chest X-ray (CXR) for diagnostic accuracy. In this study, COVID-positive patients are most likely to show B lines and sub-pleural consolidations on LUS examination.
Keywords: COVID-19; SARS-CoV-2; lung ultrasound; point-of-care.