tetano
Editor, Senior Moderator
J Transl Int Med
. 2021 Sep 28;9(3):152-160.
doi: 10.2478/jtim-2021-0016. eCollection 2021 Sep.
Cardiovascular Involvement in Patients with 2019 Novel Coronavirus Disease
Chenze Li[SUP] 1 [/SUP], Dao Wen Wang[SUP] 2 [/SUP], Chunxia Zhao[SUP] 2 [/SUP]
Affiliations
Abstract
2019 novel coronavirus disease (COVID-19) is caused by the infection of severe acute respiratory syndrome novel coronavirus (SARS-CoV-2). It is characterized by substantial respiratory symptoms and complicated with widespread other organ injuries. Cardiovascular impairment is one of the notable extrapulmonary manifestations, in terms of the deterioration of pre-existing cardiovascular diseases and newly onset acute events. We hereby review the high-quality reports about cardiovascular involvement in COVID-19 and summarize the main clinical characteristics of cardiac relevance for the all the first line clinical physicians. Additionally, the possible underlying mechanisms and the rationale for the application of specific medications, such as renin-angiotensin-aldosterone system inhibitors and hydroxychloroquine are also discussed.
Keywords: 2019 novel coronavirus disease; cardiovascular system; injuries.
. 2021 Sep 28;9(3):152-160.
doi: 10.2478/jtim-2021-0016. eCollection 2021 Sep.
Cardiovascular Involvement in Patients with 2019 Novel Coronavirus Disease
Chenze Li[SUP] 1 [/SUP], Dao Wen Wang[SUP] 2 [/SUP], Chunxia Zhao[SUP] 2 [/SUP]
Affiliations
- PMID: 34900625
- PMCID: PMC8629421
- DOI: 10.2478/jtim-2021-0016
Abstract
2019 novel coronavirus disease (COVID-19) is caused by the infection of severe acute respiratory syndrome novel coronavirus (SARS-CoV-2). It is characterized by substantial respiratory symptoms and complicated with widespread other organ injuries. Cardiovascular impairment is one of the notable extrapulmonary manifestations, in terms of the deterioration of pre-existing cardiovascular diseases and newly onset acute events. We hereby review the high-quality reports about cardiovascular involvement in COVID-19 and summarize the main clinical characteristics of cardiac relevance for the all the first line clinical physicians. Additionally, the possible underlying mechanisms and the rationale for the application of specific medications, such as renin-angiotensin-aldosterone system inhibitors and hydroxychloroquine are also discussed.
Keywords: 2019 novel coronavirus disease; cardiovascular system; injuries.