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J Pediatric Infect Dis Soc . Neutralizing Immunity Against Antigenically Advanced Omicron BA.5 in Children After SARS-CoV-2 Infection

tetano

tetano

Editor, Senior Moderator
J Pediatric Infect Dis Soc


. 2023 Dec 23:piad109.
doi: 10.1093/jpids/piad109. Online ahead of print. Neutralizing Immunity Against Antigenically Advanced Omicron BA.5 in Children After SARS-CoV-2 Infection

Edward A Belongia[SUP] 1 [/SUP], Joshua G Petrie[SUP] 1 [/SUP], Leora R Feldstein[SUP] 2 [/SUP], Lizheng Guan[SUP] 3 [/SUP], Peter J Halfmann[SUP] 3 [/SUP], Jennifer P King[SUP] 1 [/SUP], Gabriele Neumann[SUP] 3 [/SUP], David Pattinson[SUP] 3 [/SUP], Melissa A Rolfes[SUP] 4 [/SUP], Huong Q McLean[SUP] 1 [/SUP], Yoshihiro Kawaoka[SUP] 3 [/SUP]



Affiliations
Abstract

We assessed serum neutralization of Omicron BA.5 in children following SARS-CoV-2 infection during the Delta or Omicron BA.1/BA.2 variant period. Convalescent BA.5 titers were higher following infections during the Omicron BA.1/BA.2 vs Delta variant period, and in vaccinated vs unvaccinated children. Titers against BA.5 did not differ by age group.

Keywords: Omicron; SARS-CoV-2 infection; cross-neutralization; neutralizing antibodies.

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