tetano
Editor, Senior Moderator
J Pediatric Infect Dis Soc
. 2020 Dec 10;piaa164.
doi: 10.1093/jpids/piaa164. Online ahead of print.
A Surge in Pediatric Coronavirus Disease 2019 Cases: The Experience of Texas Children's Hospital from March to June 2020
Catherine E Foster[SUP] 1 2 [/SUP], Lucila Marquez[SUP] 1 2 [/SUP], Andrea L Davis[SUP] 2 [/SUP], Elizabeth Tocco[SUP] 2 [/SUP], Tjin H Koy[SUP] 2 [/SUP], James Dunn[SUP] 3 [/SUP], Paula A Revell[SUP] 3 [/SUP], Amy S Arrington[SUP] 4 [/SUP], Judith R Campbell[SUP] 1 2 [/SUP]
Affiliations
Abstract
Background: An understanding of the clinical characteristics of children with coronavirus disease 2019 in diverse communities is needed to optimize the response of healthcare providers during this pandemic.
Methods: We performed a retrospective review of all children presenting to the Texas Children's Hospital system with testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from March 10, 2020 through June 28, 2020.Demographics were recorded for all patients undergoing testing and clinical characteristics and outcomes were recorded for children with positive tests.
Results: Of 16,554 unique patients ≤ 21 years of age who were tested for SARS-CoV-2, 1215 (7.3%) patients tested positive. Infants under 1 year of age and patients aged 18-21 years had the highest percent of positive tests at 9.9% (230/2329) and 10.7% (79/739), respectively. Hispanic children accounted for 66% (802/1215) of positive tests, though they only represented 42.1% (6972/16554) of all children tested for SARS-CoV-2. Of the 1215 children with a positive test, 55.7% had fever, 40.9% had cough, 39.8% had congestion or rhinorrhea, 21.9% had gastrointestinal complaints, and 15.9% were asymptomatic. Only 97 (8%) patients were hospitalized (of which 68% were Hispanic). Most hospitalized patients had underlying medical conditions (62/97, 63.9%), including obesity. Thirty-one hospitalized patients (31/97, 32%) required respiratory support and nine patients (9/97, 9.3%) received SARS-CoV-2 antiviral therapy. Two patients died.
Conclusions: A relatively high percentage of Hispanic children tested positive for SARS-CoV-2 and were hospitalized. Most children with detection of SARS-CoV-2 had uncomplicated illness courses, some children were critically ill, and two patients died.
Keywords: Children; SARS-CoV-2; coronavirus disease 2019.
. 2020 Dec 10;piaa164.
doi: 10.1093/jpids/piaa164. Online ahead of print.
A Surge in Pediatric Coronavirus Disease 2019 Cases: The Experience of Texas Children's Hospital from March to June 2020
Catherine E Foster[SUP] 1 2 [/SUP], Lucila Marquez[SUP] 1 2 [/SUP], Andrea L Davis[SUP] 2 [/SUP], Elizabeth Tocco[SUP] 2 [/SUP], Tjin H Koy[SUP] 2 [/SUP], James Dunn[SUP] 3 [/SUP], Paula A Revell[SUP] 3 [/SUP], Amy S Arrington[SUP] 4 [/SUP], Judith R Campbell[SUP] 1 2 [/SUP]
Affiliations
- PMID: 33301595
- DOI: 10.1093/jpids/piaa164
Abstract
Background: An understanding of the clinical characteristics of children with coronavirus disease 2019 in diverse communities is needed to optimize the response of healthcare providers during this pandemic.
Methods: We performed a retrospective review of all children presenting to the Texas Children's Hospital system with testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from March 10, 2020 through June 28, 2020.Demographics were recorded for all patients undergoing testing and clinical characteristics and outcomes were recorded for children with positive tests.
Results: Of 16,554 unique patients ≤ 21 years of age who were tested for SARS-CoV-2, 1215 (7.3%) patients tested positive. Infants under 1 year of age and patients aged 18-21 years had the highest percent of positive tests at 9.9% (230/2329) and 10.7% (79/739), respectively. Hispanic children accounted for 66% (802/1215) of positive tests, though they only represented 42.1% (6972/16554) of all children tested for SARS-CoV-2. Of the 1215 children with a positive test, 55.7% had fever, 40.9% had cough, 39.8% had congestion or rhinorrhea, 21.9% had gastrointestinal complaints, and 15.9% were asymptomatic. Only 97 (8%) patients were hospitalized (of which 68% were Hispanic). Most hospitalized patients had underlying medical conditions (62/97, 63.9%), including obesity. Thirty-one hospitalized patients (31/97, 32%) required respiratory support and nine patients (9/97, 9.3%) received SARS-CoV-2 antiviral therapy. Two patients died.
Conclusions: A relatively high percentage of Hispanic children tested positive for SARS-CoV-2 and were hospitalized. Most children with detection of SARS-CoV-2 had uncomplicated illness courses, some children were critically ill, and two patients died.
Keywords: Children; SARS-CoV-2; coronavirus disease 2019.