tetano
Editor, Senior Moderator
J Pediatric Infect Dis Soc
. 2020 Aug 25;piaa099.
doi: 10.1093/jpids/piaa099. Online ahead of print.
A Pediatric Infectious Disease Perspective of SARS-CoV-2 and COVID-19 in Children
Andi L Shane[SUP] 1 [/SUP], Alice I Sato[SUP] 2 [/SUP], Carol Kao[SUP] 1 [/SUP], Felice C Adler-Shohet[SUP] 3 [/SUP], Surabhi B Vora[SUP] 4 [/SUP], Jeff Ery[SUP] 1 [/SUP], J Auletta[SUP] 5 [/SUP], Sharon Nachman[SUP] 6 [/SUP], Vanessa N Raabe[SUP] 7 [/SUP], Kengo Inagaki[SUP] 8 [/SUP], Ibukunoluwa C Akinboyo[SUP] 9 [/SUP], Charles Woods[SUP] 10 [/SUP], Abdulsalam O Alsulami[SUP] 11 [/SUP], Mundeep K Kainth[SUP] 12 [/SUP], Roberto Parulan Santos[SUP] 13 [/SUP], Claudia M Espinosa[SUP] 14 [/SUP], Julianne E Burns[SUP] 15 [/SUP], Coleen K Cunningham[SUP] 9 [/SUP], Samuel R Dominguez[SUP] 16 [/SUP], Beatriz Larru Martinez[SUP] 17 [/SUP], Frank Zhu[SUP] 18 [/SUP], Jonathan Crews[SUP] 19 [/SUP], Taito Kitano[SUP] 20 [/SUP], Lisa Saiman[SUP] 21 [/SUP], Karen Kotloff[SUP] 22 [/SUP]
Affiliations
Abstract
Understanding the role that children play in the clinical burden and propagation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for novel coronavirus (COVID-19) infections is emerging. While the severe manifestations and acute clinical burden of COVID-19 has largely spared children compared to adults, understanding the epidemiology, clinical presentation, diagnostics, management, and prevention opportunities as well as the social and behavioral impacts on child health is vital. Foremost is clarifying the contribution of asymptomatic and mild infections to transmission within the household and community and the clinical and epidemiologic significance of uncommon severe post-infectious complications. Herein we summarize the current knowledge, identify useful resources, and outline research opportunities. Pediatric infectious disease clinicians have a unique opportunity to advocate for the inclusion of children in epidemiological, clinical, treatment and prevention studies to optimize their care, as well as to represent children in the development of guidance and policy during pandemic response.
Keywords: COVID-19; SARS-CoV-2; children; novel coronavirus; pediatrics.
. 2020 Aug 25;piaa099.
doi: 10.1093/jpids/piaa099. Online ahead of print.
A Pediatric Infectious Disease Perspective of SARS-CoV-2 and COVID-19 in Children
Andi L Shane[SUP] 1 [/SUP], Alice I Sato[SUP] 2 [/SUP], Carol Kao[SUP] 1 [/SUP], Felice C Adler-Shohet[SUP] 3 [/SUP], Surabhi B Vora[SUP] 4 [/SUP], Jeff Ery[SUP] 1 [/SUP], J Auletta[SUP] 5 [/SUP], Sharon Nachman[SUP] 6 [/SUP], Vanessa N Raabe[SUP] 7 [/SUP], Kengo Inagaki[SUP] 8 [/SUP], Ibukunoluwa C Akinboyo[SUP] 9 [/SUP], Charles Woods[SUP] 10 [/SUP], Abdulsalam O Alsulami[SUP] 11 [/SUP], Mundeep K Kainth[SUP] 12 [/SUP], Roberto Parulan Santos[SUP] 13 [/SUP], Claudia M Espinosa[SUP] 14 [/SUP], Julianne E Burns[SUP] 15 [/SUP], Coleen K Cunningham[SUP] 9 [/SUP], Samuel R Dominguez[SUP] 16 [/SUP], Beatriz Larru Martinez[SUP] 17 [/SUP], Frank Zhu[SUP] 18 [/SUP], Jonathan Crews[SUP] 19 [/SUP], Taito Kitano[SUP] 20 [/SUP], Lisa Saiman[SUP] 21 [/SUP], Karen Kotloff[SUP] 22 [/SUP]
Affiliations
- PMID: 32840614
- DOI: 10.1093/jpids/piaa099
Abstract
Understanding the role that children play in the clinical burden and propagation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for novel coronavirus (COVID-19) infections is emerging. While the severe manifestations and acute clinical burden of COVID-19 has largely spared children compared to adults, understanding the epidemiology, clinical presentation, diagnostics, management, and prevention opportunities as well as the social and behavioral impacts on child health is vital. Foremost is clarifying the contribution of asymptomatic and mild infections to transmission within the household and community and the clinical and epidemiologic significance of uncommon severe post-infectious complications. Herein we summarize the current knowledge, identify useful resources, and outline research opportunities. Pediatric infectious disease clinicians have a unique opportunity to advocate for the inclusion of children in epidemiological, clinical, treatment and prevention studies to optimize their care, as well as to represent children in the development of guidance and policy during pandemic response.
Keywords: COVID-19; SARS-CoV-2; children; novel coronavirus; pediatrics.