tetano
Editor, Senior Moderator
J Pediatr Intensive Care
. 2020 Sep;9(3):222-224.
doi: 10.1055/s-0040-1705182. Epub 2020 Mar 6.
Acute Necrotizing Encephalopathy of Childhood with H1N1 Infection
Lalit Takia[SUP] 1 [/SUP], Nilamani Patra[SUP] 1 [/SUP], Karthi Nallasamy[SUP] 1 [/SUP], Lokesh Saini[SUP] 2 [/SUP], Renu Suthar[SUP] 2 [/SUP], Suresh K Angurana[SUP] 1 [/SUP], Muralidharan Jayashree[SUP] 1 [/SUP]
Affiliations
Abstract
Acute necrotizing encephalopathy of childhood (ANEC) is an uncommon and fulminant complication of seasonal influenza infection associated with high mortality and poor neurological outcome. We report a 4.5-year-old female who had pneumonia, ANEC, and raised intracranial pressure (ICP) with polymerase chain reaction proven H1N1 infection. Management included mechanical ventilation, invasive monitoring and control of ICP, oseltamivir, methylprednisolone, and supportive care in pediatric intensive care unit. She survived with poor neurological status at discharge.
Keywords: H1N1 influenza; encephalopathy; raised ICP.
. 2020 Sep;9(3):222-224.
doi: 10.1055/s-0040-1705182. Epub 2020 Mar 6.
Acute Necrotizing Encephalopathy of Childhood with H1N1 Infection
Lalit Takia[SUP] 1 [/SUP], Nilamani Patra[SUP] 1 [/SUP], Karthi Nallasamy[SUP] 1 [/SUP], Lokesh Saini[SUP] 2 [/SUP], Renu Suthar[SUP] 2 [/SUP], Suresh K Angurana[SUP] 1 [/SUP], Muralidharan Jayashree[SUP] 1 [/SUP]
Affiliations
- PMID: 32685254
- PMCID: PMC7360391 (available on 2021-09-01)
- DOI: 10.1055/s-0040-1705182
Abstract
Acute necrotizing encephalopathy of childhood (ANEC) is an uncommon and fulminant complication of seasonal influenza infection associated with high mortality and poor neurological outcome. We report a 4.5-year-old female who had pneumonia, ANEC, and raised intracranial pressure (ICP) with polymerase chain reaction proven H1N1 infection. Management included mechanical ventilation, invasive monitoring and control of ICP, oseltamivir, methylprednisolone, and supportive care in pediatric intensive care unit. She survived with poor neurological status at discharge.
Keywords: H1N1 influenza; encephalopathy; raised ICP.