tetano
Editor, Senior Moderator
J Obstet Gynaecol Res
. 2022 May 23.
doi: 10.1111/jog.15302. Online ahead of print.
Intrauterine fetal death during COVID-19 pregnancy: Typical fetal heart rate changes, coagulopathy, and placentitis
Maya Kato[SUP] 1 [/SUP], Kyohei Yamaguchi[SUP] 1 [/SUP], Yuka Maegawa[SUP] 1 [/SUP], Shihoko Komine-Aizawa[SUP] 2 [/SUP], Eiji Kondo[SUP] 3 [/SUP], Tomoaki Ikeda[SUP] 3 [/SUP]
Affiliations
Abstract
Although various perinatal outcomes in coronavirus disease 2019 (COVID-19) pregnancies have been reported, the fetal and neonatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain unclear. Several reports of miscarriages and stillbirths have been recorded, but vertical transmission by SARS-CoV-2 is considered very rare, and the cause remains unknown. We report a case of a 22-year-old uncomplicated Japanese woman infected with SARS-CoV-2 during the second trimester, resulting in intrauterine fetal death due to placental insufficiency associated with COVID-19 placentitis. This report emphasizes the importance of longitudinal assessment of fetal well-being by fetal heart rate monitoring and early detection of maternal coagulation dysfunction representing SARS-CoV-2 inflammation to manage COVID-19 in pregnancy.
Keywords: coronavirus disease 2019; fetal heart rate monitoring; intrauterine fetal death; placentitis; pregnancy; severe acute respiratory syndrome coronavirus 2.
. 2022 May 23.
doi: 10.1111/jog.15302. Online ahead of print.
Intrauterine fetal death during COVID-19 pregnancy: Typical fetal heart rate changes, coagulopathy, and placentitis
Maya Kato[SUP] 1 [/SUP], Kyohei Yamaguchi[SUP] 1 [/SUP], Yuka Maegawa[SUP] 1 [/SUP], Shihoko Komine-Aizawa[SUP] 2 [/SUP], Eiji Kondo[SUP] 3 [/SUP], Tomoaki Ikeda[SUP] 3 [/SUP]
Affiliations
- PMID: 35605975
- DOI: 10.1111/jog.15302
Abstract
Although various perinatal outcomes in coronavirus disease 2019 (COVID-19) pregnancies have been reported, the fetal and neonatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain unclear. Several reports of miscarriages and stillbirths have been recorded, but vertical transmission by SARS-CoV-2 is considered very rare, and the cause remains unknown. We report a case of a 22-year-old uncomplicated Japanese woman infected with SARS-CoV-2 during the second trimester, resulting in intrauterine fetal death due to placental insufficiency associated with COVID-19 placentitis. This report emphasizes the importance of longitudinal assessment of fetal well-being by fetal heart rate monitoring and early detection of maternal coagulation dysfunction representing SARS-CoV-2 inflammation to manage COVID-19 in pregnancy.
Keywords: coronavirus disease 2019; fetal heart rate monitoring; intrauterine fetal death; placentitis; pregnancy; severe acute respiratory syndrome coronavirus 2.
