tetano
Editor, Senior Moderator
J Neurovirol
. 2021 Jan 18.
doi: 10.1007/s13365-020-00934-0. Online ahead of print.
Magnetic resonance imaging features of COVID-19-related cranial nerve lesions
Diogo Goulart Corr?a[SUP] 1 2 [/SUP], Luiz Celso Hygino da Cruz Jr[SUP] 3 4 [/SUP], Fernanda Cristina Rueda Lopes[SUP] 3 4 [/SUP], Cl?udio de Carvalho Rangel[SUP] 3 4 [/SUP], Anna Luiza de Ara?jo Henriques Tessarollo[SUP] 4 [/SUP], Karla Cristina Godeiro Coelho[SUP] 4 [/SUP], Rafael Zandonadi Brand?o[SUP] 4 [/SUP], Ricardo Augusto Faro Novis[SUP] 4 [/SUP], Shenia Sbardellotto Colnaghi Novis[SUP] 4 [/SUP], Rodrigo Silveira[SUP] 4 5 [/SUP], Viviane T Carvalho[SUP] 4 5 [/SUP], Osvaldo J M Nascimento[SUP] 4 5 [/SUP]
Affiliations
Abstract
The complete features of the neurological complications of coronavirus disease 2019 (COVID-19) still need to be elucidated, including associated cranial nerve involvement. In the present study we describe cranial nerve lesions seen in magnetic resonance imaging (MRI) of six cases of confirmed COVID-19, involving the olfactory bulb, optic nerve, abducens nerve, and facial nerve. Cranial nerve involvement was associated with COVID-19, but whether by direct viral invasion or autoimmunity needs to be clarified. The development of neurological symptoms after initial respiratory symptoms and the absence of the virus in the cerebrospinal fluid (CSF) suggest the possibility of autoimmunity.
Keywords: COVID-19; Cranial nerves; MRI; SARS-CoV-2.
. 2021 Jan 18.
doi: 10.1007/s13365-020-00934-0. Online ahead of print.
Magnetic resonance imaging features of COVID-19-related cranial nerve lesions
Diogo Goulart Corr?a[SUP] 1 2 [/SUP], Luiz Celso Hygino da Cruz Jr[SUP] 3 4 [/SUP], Fernanda Cristina Rueda Lopes[SUP] 3 4 [/SUP], Cl?udio de Carvalho Rangel[SUP] 3 4 [/SUP], Anna Luiza de Ara?jo Henriques Tessarollo[SUP] 4 [/SUP], Karla Cristina Godeiro Coelho[SUP] 4 [/SUP], Rafael Zandonadi Brand?o[SUP] 4 [/SUP], Ricardo Augusto Faro Novis[SUP] 4 [/SUP], Shenia Sbardellotto Colnaghi Novis[SUP] 4 [/SUP], Rodrigo Silveira[SUP] 4 5 [/SUP], Viviane T Carvalho[SUP] 4 5 [/SUP], Osvaldo J M Nascimento[SUP] 4 5 [/SUP]
Affiliations
- PMID: 33460014
- DOI: 10.1007/s13365-020-00934-0
Abstract
The complete features of the neurological complications of coronavirus disease 2019 (COVID-19) still need to be elucidated, including associated cranial nerve involvement. In the present study we describe cranial nerve lesions seen in magnetic resonance imaging (MRI) of six cases of confirmed COVID-19, involving the olfactory bulb, optic nerve, abducens nerve, and facial nerve. Cranial nerve involvement was associated with COVID-19, but whether by direct viral invasion or autoimmunity needs to be clarified. The development of neurological symptoms after initial respiratory symptoms and the absence of the virus in the cerebrospinal fluid (CSF) suggest the possibility of autoimmunity.
Keywords: COVID-19; Cranial nerves; MRI; SARS-CoV-2.