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J Neurosurg Case Lessons . Cerebral vasculopathy and strokes in a child with COVID-19 antibodies: illustrative case

tetano

Editor, Senior Moderator
J Neurosurg Case Lessons


. 2021 Jul 19;2(3):CASE21160.
doi: 10.3171/CASE21160.
Cerebral vasculopathy and strokes in a child with COVID-19 antibodies: illustrative case


Chase H Foster[SUP] 1 [/SUP], Anthony J Vargas[SUP] 2 [/SUP], Elizabeth Wells[SUP] 3 [/SUP], Robert F Keating[SUP] 1 4 [/SUP], Suresh N Magge[SUP] 2 4 [/SUP]



Affiliations

Abstract

Background: The ability of coronavirus disease 2019 (COVID-19) to cause neurological insults in afflicted adults is becoming increasingly understood by way of an ever-growing amount of international data. By contrast, the pandemic illness's neurological effects in the pediatric population are both poorly understood and sparsely reported.
Observations: In this case, the authors reported their experience with a preschool-age child with hydrocephalus who suffered multiterritory strokes presumed secondary to immune-mediated cerebral vasculopathy as a result of asymptomatic COVID-19 infection.
Lessons: Growing evidence indicates that COVID-19 can cause neurological sequelae such as encephalitis and strokes. In this case report, the authors discussed a case of cerebral vasculopathy and strokes in a pediatric patient who was positive for COVID-19.

Keywords: COVID-19; COVID-19 = coronavirus disease 2019; CSF = cerebrospinal fluid; CT = computed tomography; CoV-S = COVID-19–related stroke; EVD = external ventricular drain; IL = interleukin; IgG = immunoglobulin G; MRA = magnetic resonance angiography; MRI = magnetic resonance imaging; PAI-1 = plasminogen activator inhibitor type 1; PCR = polymerase chain reaction; SARS-CoV-2 = severe acute respiratory syndrome coronavirus-2; cerebral vasculopathy; pediatric; stroke.
 
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