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J Neurol . Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature

tetano

Editor, Senior Moderator
J Neurol


. 2021 Sep 5.
doi: 10.1007/s00415-021-10785-2. Online ahead of print.
Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature


Erum Khan[SUP] 1 2 [/SUP], Ashish K Shrestha[SUP] 2 [/SUP], Mark A Colantonio[SUP] 3 [/SUP], Richard N Liberio[SUP] 3 [/SUP], Shitiz Sriwastava[SUP] 4 5 [/SUP]



Affiliations

Abstract

Objective: To report a unique case and literature review of post COVID-19 vaccination associated transverse myelitis and with abnormal MRI findings.
Background: Coronavirus disease have been reported to be associated with several neurological manifestations such as stroke, Guillain-Barré syndrome, meningoencephalitis amongst others. There are only a few reported cases of transverse myelitis with the novel coronavirus (n-CoV-2). Here, we identify a post COVID-19 vaccination patient diagnosed with acute transverse myelitis.
Method: A retrospective chart review of a patient diagnosed with post SARS-CoV-2 vaccination acute transverse myelitis, and a review of literature of all the reported cases of other post vaccination and transverse myelitis, from December 1st, 2010 till July 15th, 2021, was performed.
Conclusion: To our knowledge, this is the one of early reported case of transverse myelitis and with post SARS-CoV-2 vaccination, who responded well to plasmapheresis. Further studies would be recommended to identify the underlying correlation between COVID-19 vaccination and transverse myelitis.

Keywords: COVID-19; MRI spine; Post vaccination myelitis; SARS-CoV-2; Transverse myelitis.
 
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