tetano
Editor, Senior Moderator
J Neuroimmunol
. 2021 Jun 30;358:577655.
doi: 10.1016/j.jneuroim.2021.577655. Online ahead of print.
Complex movement disorders in SARS-CoV-2 infection induced acute disseminated encephalomyelitis
Ritwik Ghosh[SUP] 1 [/SUP], Souvik Dubey[SUP] 2 [/SUP], Arpan Mandal[SUP] 1 [/SUP], Biman Kanti Ray[SUP] 2 [/SUP], Julián Benito-León[SUP] 3 [/SUP]
Affiliations
Abstract
Movement disorders are extremely rare in acute disseminated encephalomyelitis (ADEM) and in the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. We herein report a 34-years-old previously healthy woman who presented with a febrile illness and a constellation of movement disorders (predominantly myoclonus) followed by encephalopathy. After exclusion of common infectious, autoimmune and paraneoplastic etiologies, she was diagnosed to have COVID-19 induced ADEM, which responded to intravenous methylprednisolone and intravenous immunoglobulin. Our case adds to the tally of cases of post-SARS-CoV-2 infection related movement disorders and to the exceedingly rare list of cases in which movement disorders preceded ADEM.
Keywords: ADEM; Acute disseminated encephalomyelitis; COVID-19; Movement disorders; Myoclonus; SARS-CoV-2.
. 2021 Jun 30;358:577655.
doi: 10.1016/j.jneuroim.2021.577655. Online ahead of print.
Complex movement disorders in SARS-CoV-2 infection induced acute disseminated encephalomyelitis
Ritwik Ghosh[SUP] 1 [/SUP], Souvik Dubey[SUP] 2 [/SUP], Arpan Mandal[SUP] 1 [/SUP], Biman Kanti Ray[SUP] 2 [/SUP], Julián Benito-León[SUP] 3 [/SUP]
Affiliations
- PMID: 34265625
- DOI: 10.1016/j.jneuroim.2021.577655
Abstract
Movement disorders are extremely rare in acute disseminated encephalomyelitis (ADEM) and in the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. We herein report a 34-years-old previously healthy woman who presented with a febrile illness and a constellation of movement disorders (predominantly myoclonus) followed by encephalopathy. After exclusion of common infectious, autoimmune and paraneoplastic etiologies, she was diagnosed to have COVID-19 induced ADEM, which responded to intravenous methylprednisolone and intravenous immunoglobulin. Our case adds to the tally of cases of post-SARS-CoV-2 infection related movement disorders and to the exceedingly rare list of cases in which movement disorders preceded ADEM.
Keywords: ADEM; Acute disseminated encephalomyelitis; COVID-19; Movement disorders; Myoclonus; SARS-CoV-2.