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J Neuroeng Rehabil . The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neur

tetano

Editor, Senior Moderator
J Neuroeng Rehabil


. 2022 Oct 8;19(1):108.
doi: 10.1186/s12984-022-01089-1.
The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor


Colin K Franz[SUP] 1 2 3 4 [/SUP], Nikhil K Murthy[SUP] 5 6 [/SUP], George R Malik[SUP] 7 [/SUP], Jean W Kwak[SUP] 8 9 [/SUP], Dom D'Andrea[SUP] 10 [/SUP], Alexis R Wolfe[SUP] 5 11 [/SUP], Ellen Farr[SUP] 12 [/SUP], Melanie A Stearns[SUP] 13 [/SUP], Swati Deshmukh[SUP] 14 [/SUP], Jinny O Tavee[SUP] 15 [/SUP], Fang Sun[SUP] 16 [/SUP], Kevin N Swong[SUP] 6 [/SUP], Leslie Rydberg[SUP] 10 17 [/SUP], R James Cotton[SUP] 10 17 [/SUP], Lisa F Wolfe[SUP] 10 16 11 [/SUP], James M Walter[SUP] 11 [/SUP], John M Coleman 3rd[SUP] 16 11 [/SUP], John A Rogers[SUP] 8 6 9 18 19 20 21 [/SUP]



Affiliations

Abstract

We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine this new data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of the feasibility for a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting.

Keywords: Brachial plexus; COVID-19; Intensive care unit; Neuromuscular; Neuropathy; Peripheral nerve injury; Rehabilitation; Wearable sensor.
 
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